Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jo991666i | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Unlocking Germanium Potential: Stabilization Strategies Through Wet Chemical Functionalization.
Materials (Basel)
December 2024
Istituto di Scienze e Tecnologie Chimiche "Giulio Natta"-SCITEC-CNR, Via Corti, 20132 Milan, Italy.
Germanium (Ge) has long been recognized for its superior carrier mobility and narrower band gap compared to silicon, making it a promising candidate in microelectronics and optoelectronics. The recent demonstration of good biocompatibility, combined with the ability to selectively functionalize its surface, establishes the way for its use in biosensing and bioimaging. This review provides a comprehensive analysis of the most recent advancements in the wet chemical functionalization of germanium surfaces.
View Article and Find Full Text PDFIon Hydration Enables Generality in Asymmetric Catalysis: Desymmetrization to P-Stereogenic Triarylphosphine Derivatives.
Angew Chem Int Ed Engl
December 2024
National University of Singapore Department of Chemistry, Department of Chemistry, 3 Science Drive 3, 117543, Singapore, SINGAPORE.
Asymmetric synthesis relies on seamless transmission of stereochemical information from a chiral reagent/catalyst to a prochiral substrate. The disruption by substrates' structural changes presents a hurdle in innovating generality-oriented asymmetric catalysis. Here, we report a strategy for substrate adaptability by exploiting a fundamental physicochemical phenomenon-ion hydration, in developing remote desymmetrization to access P-stereogenic triarylphosphine oxides and sulfides.
View Article and Find Full Text PDFConvenient lanthanum-mediated synthesis of bulky -alkyl amines from nitriles.
Chem Commun (Camb)
December 2024
Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada.
-alkyl amines can be conveniently prepared in one step from nitriles by a double addition of ethyl or propyl Grignard reagent mediated by a commercially available lanthanum chloride-lithium chloride complex solution. The reaction operates on a variety of benzonitriles, with several heterocyclic nitriles and an alkyl nitrile also being suitable substrates.
View Article and Find Full Text PDFThermodynamics of Micelle Formation of Selected Homologous 7-Alkyl Derivatives of Na-Cholate in Aqueous Solution: Steroid Skeleton and the Alkyl Chain Conformation.
Int J Mol Sci
December 2024
Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljka 3, 21000 Novi Sad, Serbia.
Bile acid salts are steroid biosurfactants that build relatively small micelles compared to surfactants with an alkyl chain due to the rigid conformation of the steroid skeleton. In order to increase the capacity of micellar solubilization of the hydrophobic molecular guest, certain C7 alkyl derivatives were synthesized. Namely, introducing an alkyl group in the C7 position of the steroid skeleton results in a more effective increase in the micelle's hydrophobic domain (core) than the introduction in the C3 position.
View Article and Find Full Text PDFSynthesis of Consecutive All-Carbon Quaternary Centers via Three-Step Reactions.
Org Lett
December 2024
Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai, Miyagi 980-8578, Japan.
Consecutive all-carbon quaternary centers were synthesized in three steps from the corresponding ketones. The three reactions were (1) Knoevenagel condensation of ketone and malononitrile to afford dicyanoalkene, (2) 1,4-addition reaction of a Grignard reagent to dicyanoalkene, and (3) oxidative transformation of a malononitrile moiety to an ester, thioester, amide, and α-nitroketone. This method was applied to the synthesis of 17α-methyl steroids with a good yield and excellent diastereoselectivity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!