The article reports two cases of childhood autism in tuberous sclerosis (TS). Certain atypical features are highlighted. The probands did not show the common seizure types associated with either TS or autism. No ventricular dilatation, cerebral atrophy or temporal lobe involvement was evident. The high prevalence of childhood autism in TS probands with moderate to severe mental retardation has been emphasized.
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http://dx.doi.org/10.1007/BF02730908 | DOI Listing |
Rev Environ Health
March 2025
Public Health Department- Dubai Health Authority, Dubai, United Arab Emirates.
Introduction: The developing brain, especially vulnerable during neuroplastic phases, is influenced by environmental and genetic factors. Understanding the impacts of air pollution on children's and young adults' mental health is an emerging research field.
Content: This review systematically examines the adverse associations of ambient air pollutants on mental health.
Rev Bras Enferm
March 2025
Universidade Federal do Rio de Janeiro. Rio de Janeiro, Rio de Janeiro, Brazil.
Objectives: to understand nurse participation in the process of early detection of warning signs of autism spectrum disorders (ASD) in childcare consultations.
Methods: qualitative, exploratory research, conducted through semi-structured interviews conducted between August and November 2022 with 27 nurses from family clinics in the city of Rio de Janeiro. The IRaMuTeQ® software was used for data treatment.
JAMA Psychiatry
March 2025
Center for Neuropsychiatric Schizophrenia Research (CNSR& Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS), Mental Health Centre Glostrup, Copenhagen University Hospital - Mental Health Services CPH, Copenhagen, Denmark.
Importance: Maternal inflammation during pregnancy has been associated with an increased risk of neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD) and autism, and cognitive deficits in early childhood. However, little is known about the contributions of a wider range of inflammatory proteins to this risk.
Objective: To determine whether maternal inflammatory proteins during pregnancy are associated with the risk of NDDs and executive functions (EF) in middle childhood and to identify protein patterns associated with NDDs and EF.
Actas Esp Psiquiatr
March 2025
Department of Pediatric, The First People's Hospital of Taizhou, 318020 Taizhou, Zhejiang, China.
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and limited behavior. Despite the association of numerous synaptic gene mutations with ASD, the presence of behavioral abnormalities in mice expressing autism-associated R617W mutation in synaptic adhesion protein neuroligin-3 (NL3) has not been established. This work focuses on establishing a mouse model of ASD caused by NL3 R617W missense mutation (NL3R617W) and characterizing and profiling the molecular as well as behavioral features of the animal model.
View Article and Find Full Text PDFNed Tijdschr Geneeskd
March 2025
Karakter, Kinder- en Jeugpsychiatrie, meerdere locaties.
Autism is classified based on the behavior and development of a child or adult. Subjective assessment plays a significant role during the diagnostic process. Recently, various methods have been developed to enhance diagnostic procedures with more objective instruments.
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