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Role of inducible nitric oxide (iNOS) and nitrosative stress in regulating sex differences in secondary lymphedema.
Front Physiol
December 2024
Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Secondary lymphedema is a common complication following surgical treatment of solid tumors. Although more prevalent in women due to higher breast cancer rates, men also develop lymphedema, often with more severe manifestations. Despite these differences in clinical presentation, the cellular mechanisms underlying sex differences are poorly understood.
View Article and Find Full Text PDFCognitive Diversity for Creativity and Inclusive Growth.
Angew Chem Int Ed Engl
January 2025
Graduate School of Education, Harvard University. 6 Appian Way | Cambridge, MA, 02138, USA.
Cognitively diverse teams outperform high intelligence (IQ) teams in problem solving, while businesses with at least one woman in their board of directors financially outperform ones with all men boards. These well-known facts are lost in most academic science enterprises. Herein, we make the case for looking at sources, approaches, and opportunities in expanding cognitive diversity of research teams for high productivity and efficiency.
View Article and Find Full Text PDFLookism, a Leak in the Career Pipeline? Career Perspective Consequences of Lookism Climate and Workplace Incivility.
Behav Sci (Basel)
October 2024
Department of Psychology and Cognitive Science, University of Trento, 38068 Rovereto, Italy.
Despite strides toward gender equality in the workforce, women continue to face significant challenges, including the "glass ceiling" and the "leaky pipeline", partially stemming from low occupational self-confidence. This study examined whether a climate of lookism leads to workplace mistreatment, undermining employees' perceptions of job competence and career potential, with a focus on gender differences. Using a cross-sectional design, data from 699 Italian workers (42.
View Article and Find Full Text PDFThe conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis.
Elife
October 2024
Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Article Synopsis
- Male germ cells across animal species share a common origin, indicating they likely follow a conserved genetic program crucial for their identity.
- The research employs network analysis of the spermatocyte transcriptome from various species to explore the evolutionary origin of male germ cells at the molecular level, revealing a core set of genes and functional associations that have been preserved through evolution.
- By disrupting male germ cell identity, the study identifies 161 new spermatogenesis-related genes and highlights their implications for human infertility, while promoting a cross-species approach that can be applied to other cell types and diseases.
Diversity, Equity, and Inclusion in Plastic Surgery: A Systematic Review.
Ann Plast Surg
April 2024
From the Swanson Center, Leawood, KS.
Background: The number of publications on the subject of diversity, equity, and inclusion has surged in the last 5 years. However, a systematic review of this topic has not been published.
Method: Six top plastic surgery journals were queried from 2018 to 2023 using the search term "diversity.
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