Primary sarcomas of the central nervous system.

Oncology

Unit of Bone and Soft Tissue Sarcomas, Department of Medicine, Institut Gustav Roussy, Villejuif, France.

Published: April 2000

AI Article Synopsis

  • The study reviewed medical files of 14 patients with primary brain and spine sarcomas, finding 10 had brain sarcomas and 4 had spinal sarcomas.
  • The tumors were likely to have originated from brain tissue, blood vessels, meninges, or spinal nerve roots, with angiosarcoma being the most common type.
  • Most patients (95%) had their brain tumors surgically removed, while radiotherapy was administered to 6 brain tumor patients and all spinal tumor patients; two patients later showed lung metastases despite initial treatment.

Article Abstract

The medical files of 14 patients with primary brain and spine sarcomas were retrospectively reviewed. Ten patients had primary brain sarcomas and 4 primary spinal sarcomas. The tumors probably originated in the brain substance or blood vessels, in the meninges or in the inner aspect of the skull. The spinal tumors originated in the nerve roots of the cauda equina and in the spinal substance or blood vessels. The most common type was angiosarcoma. Removal of the brain tumors was performed in 95% of the patients. Radiotherapy was delivered to 6 patients with brain sarcomas and to all patients with primary spinal sarcomas. Metastatic disease to the lung or pleural effusion was evident in 2 patients who underwent total removal of their tumors followed by radiation therapy.

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Source
http://dx.doi.org/10.1159/000012102DOI Listing

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