Purpose: To report a case of bilateral optic neuropathy in a patient receiving tacrolimus (FK 506, Prograf; Fujisawa USA, Inc, Deerfield, Illinois) for immunosuppression after orthotropic liver transplantation.
Method: Case report. In a 58-year-old man receiving tacrolimus after orthotropic liver transplantation, serial neuro-ophthalmologic examinations and laboratory studies were performed.
Results: The patient had episodic deterioration of vision in both eyes, with clinical features resembling ischemic optic neuropathies. Deterioration of vision occurred despite discontinuation of the tacrolimus.
Conclusion: Tacrolimus and other immunosuppressive agents may be associated with optic nerve toxicity.
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| http://dx.doi.org/10.1016/s0002-9394(99)00443-2 | DOI Listing |
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