Data available in the literature and the results of original investigations of the effect of drugs on the free-radical oxidation process are summarized. It is pointed out that the character of drug influence on the on the free-radical oxidation process must be taken into account in selecting drugs for the treatment of particular diseases.
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Food Res Int
January 2025
Sericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Products Processing, Guangdong 510610, China. Electronic address:
Health benefit effects of bioactive compounds depend on their bioavailabilities, which could vary according to factors including food matrix and digestion environment. To understand the "bioaccessible" health benefit of red pitay pulp, the INFOGEST static in vitro simulation of gastrointestinal (GI) digestion model and targeted metabolomics method were applied to unravel the fates of bioactive compounds in the whole food of red pitaya pulp during GI digestion. The antioxidant activity as one of the health benefit indices was also assessed to compare the changes in bioactive properties of red pitaya pulp.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
School of Environmental and Architecture, University of Shanghai for Science and Technology, Shanghai 200093, China. Electronic address:
Carbon dots (CDs) mediated g-CN (CN) is a promising visible-light-driven semiconductor in catalyzing peroxymonosulfate (PMS) for aqueous contaminants remediation. However, the poor dispersibility of powered catalyst and its challenging recyclability impede their broader application. Herein, we embedded FeN bridge within the g-CN framework and immobilized g-CN gel beads (CA/FNCCN) through a 3D cross-linking process with sodium alginate.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei City 11031, Taiwan; International Ph.D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan. Electronic address:
Severe traumatic bleeding and chronic diabetic wounds require rapid hemostasis and multifunctional dressings, which remain particularly challenging, especially for non-compressible trauma and irregular wounds with dysregulated microenvironments. Chitosan (CS) can be easily cross-linked with genipin to form GpCS hydrogels. However, developing injectable GpCS hydrogels for biomedical applications faces challenges, particularly in enhancing rapid gel formation and optimizing physical properties.
View Article and Find Full Text PDFFront Immunol
January 2025
College of Pharmacy, University of Houston, Houston, TX, United States.
Background: Proton pump inhibitors (PPIs) are one of the most used drugs worldwide. While generally considered safe, the usage of PPIs is associated with several adverse outcomes including acute infectious diseases. PPIs influence macrophage and neutrophil function although a systematic review has never been undertaken.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Medical Sciences, Department of Toxicology, Tarbiat Modares University, Tehran, Iran.
Breast cancer is the most common type of cancer in women worldwide. A common approach to cancer treatment in clinical practice is to use a combination of drugs to enhance the anticancer activity of drugs while reducing their side effects. In this regard, we evaluated the effectiveness of combined treatment with gemcitabine (GCB) and arsenic (ATO) and how they affect the cell death pathway in cancer cells.
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