AI Article Synopsis
- Intravascular ultrasound (IVUS) allows for detailed analysis of how well coronary stents fit and expand in blood vessels during real-time imaging.
- The assessment of neointima (tissue growth inside stents) through IVUS can evaluate new drugs designed to minimize tissue growth after stenting.
- The manuscript discusses the development of automated systems for 3D IVUS image analysis and showcases preliminary randomized trials using this technology to assess neointima in coronary stenting.
Article Abstract
Intravascular ultrasound (IVUS) permits the detailed examination of coronary stent apposition and expansion in vivo. IVUS assessment of the extent and distribution of in-stent neointima at follow-up is an ideal model for the evaluation of new antiproliferative drugs that aim at a reduced in-stent neointimal hyperplasia. Recently, automated systems for three-dimensional reconstruction and analysis of IVUS images have been developed. This manuscript illustrates the methodology and clinical use of automated three-dimensional IVUS analysis systems during coronary stenting, and highlights the first randomized trials to apply such a technique for the assessment of in-stent neointima.
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