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A battle of surgical strategies: Clinically enlarged lateral lymph nodes in patients with locally advanced rectal cancer; extended mesorectal excision (e-TME) versus traditional surgery (TME-alone) a meta-analysis.
Pathol Res Pract
March 2025
Biochemistry Dept., Faculty of Pharmacy, Ain Shams University, Abassia, Cairo 11566, Egypt. Electronic address:
Background: The infiltration of lateral lymph nodes (LLN) plays a crucial role in the staging and treatment of individuals with locally advanced rectal cancer (LARC). This meta-analysis aimed to compare the efficacy of extended mesorectal excision (eTME) versus traditional mesorectal excision (TME-alone) in patients with clinically enlarged (LLN) concomitant neoadjuvant chemoradiation.
Methods: This study is registered with PROSPERO (CRD42023457805).
Transition to lateral lymph node dissection in rectal cancer: Forty-five years of outcomes data.
Surgery
March 2025
Department of Colorectal Surgery, National Cancer Center Hospital, Tokyo, Japan.
Purpose: To determine how outcomes of lateral lymph node dissection for rectal cancer have changed over time.
Methods: This retrospective study included patients with rectal cancer without distant metastasis who underwent total mesorectal excision and lateral lymph node dissection at our institution between 1975 and 2020. We examined the association of surgical time period with relapse-free and overall survival.
Near-infrared imaging with indocyanine green fluorescence for intraoperative lymphatic assessment in rectal cancer surgery: a systematic review.
Minerva Surg
February 2025
General Surgery Department and Simulation Center, Department of Medicine, Academic Hospital of Udine, University of Udine, Udine, Italy.
Introduction: At present, harvesting more lymph nodes is considered more conducive to the prognosis of colorectal cancer surgery. The recent development of enhanced surgical visualization has led to the wide employment of indocyanine green (ICG) to assist minimally invasive surgery. This systematic review aims to provide a wide and critical overview of the current state of the art of ICG lymphography during rectal surgery, by focusing on the most relevant literature on this topic.
View Article and Find Full Text PDFLearning curve analysis for prophylactic bilateral robot-assisted lateral lymph node dissection for lower rectal cancer: a retrospective study.
Tech Coloproctol
March 2025
Department of Gastroenterological Surgery, Osaka International Cancer Institute, 69-1-3 Ootemae-Chuoku, Osaka, Osaka, 540-0008, Japan.
Background: Lateral lymph node dissection (LLND) is an important surgical procedure in the treatment of lower rectal cancer (RC). However, limited data are available regarding the learning curve for robot-assisted LLND (RA-LLND). This study aimed to evaluate the learning curve for prophylactic bilateral RA-LLND for lower RC.
View Article and Find Full Text PDFLaparoscopic Versus Robotic Lateral Pelvic Lymph Node Dissection in Locally-Advanced Rectal Cancer: A Cohort Study Comparing Perioperative Morbidity and Short-Term Oncological Outcomes.
Cancer Rep (Hoboken)
March 2025
Division of Colorectal Oncology, Department of Surgical Oncology, Tata Memorial Centre, Mumbai, India.
Background: Robotic surgery has been associated with superior short-term outcomes in patients undergoing total mesorectal excision (TME) for organ-confined rectal cancer. However, whether this approach offers an additional benefit over laparoscopy when performing lateral pelvic lymph node dissection (LPLND) with TME or extended TME (e-TME) in locally advanced rectal cancer (LARC) is not known.
Aims: This study was conducted to evaluate the outcomes of robotic and laparoscopic LPLND in patients with lateral pelvic node-positive LARC with reference to intraoperative safety, postoperative morbidity, pathological indices including nodal yield and node positivity rates, lateral pelvic recurrence rates, and short term event-free and overall survival.
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