The aim of the study was investigation of efficiency of mental activity in people with different types of vegetative regulation. The 32 operators Chernobyl atomic station aged 26-54 were examined. The mental activity was studied by two computer's tests. The registration and analysis cardio-intervals were processing in set time interval. The results of investigation are showed that efficiency of operator's activity related with quality, productivity and information processing speed. In successful operators are showed transition from determination to stochastic types of heart rhythm regulation. In non-successful operators are showed transition from stochastic to determination types of heart rhythm regulation. Thus the increase of determinate organization of heart rhythm system regulation related with changes of mental activity algorithm and with intensification of psychophysiological functions tension.
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