Low-power red laser light (LPRLL) irradiation enhances endothelial cell growth in vitro and in vivo and reduces restenosis in animal models. The present study reports the preliminary clinical experience in our center. Eighty-one patients were treated with LPRLL, 30 mW/1 min, for in-stent restenosis (n = 27), elective stenting for recurrent restenosis (n = 16), and stenting for treatment of a suboptimal PTCA result (n = 38). All interventions were successful and no major adverse events due to LPRLL therapy were observed. At follow-up, 12 patients (14.8%) underwent an early control coronarogram due to target vessel restenosis. At 6 months, another 20 patients showed a significant restenosis of the target vessel. Preliminary clinical evaluation demonstrates that LPRLL is feasible and safe. The preliminary results suggest that LPRLL results in a decrease of in-stent restenosis when used during primary stenting.
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http://dx.doi.org/10.1002/(sici)1522-726x(200004)49:4<468::aid-ccd27>3.0.co;2-y | DOI Listing |
J Lasers Med Sci
December 2024
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
The treatment of chronic testicular pain is a complex condition that will be encountered by most practicing clinicians. In this study, the influence of low-level laser irradiation of the red and infrared spectral range for treating chronic testicular pain was evaluated and compared. In this double-blind, placebo-controlled randomized clinical trial study, 60 patients were randomly divided into three groups of 20: (1) low-level laser group with red (650 nm, 50 mW), (2) low-level laser group with infrared (820 nm, 100 mW) and (3) laser placebo group.
View Article and Find Full Text PDFImmunol Med
January 2025
Department of Diabetes, Endocrinology and Clinical Immunology, Hyogo Medical University School of Medicine, Hyogo, Japan.
Rituximab (RTX) has been reported to effectively maintain remission in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). In this multicenter study involving 57 patients who achieved remission after 24 weeks, we evaluated the effectiveness of RTX in maintaining remission in patients with AAV. Patients were divided into three groups based on RTX administration: continuous, induction phase-only, and maintenance phase-only groups.
View Article and Find Full Text PDFUltrason Sonochem
January 2025
Marwadi University Research Centre, Department of Microbiology, Marwadi University, Rajkot, Gujarat 360003, India.
Escalating global protein demand necessitates the commercialization of protein rich products. Oat is a promising high-quality protein source but it requires structural and functional modifications to diversify its application. The current investigation was focused on the impact of different powers of ultrasonic waves (200, 400, and 600 W) on structural and functional characteristics of oat protein isolates to improve its techno-functional properties.
View Article and Find Full Text PDFNat Commun
December 2024
Advanced Membranes and Porous Materials Center, Division of Physical Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.
Blue energy, a clean energy source derived from salinity gradients, has recently drawn increased research attention. It can be harvested using charged membranes, typically composed of amorphous materials that suffer from low power density due to their disordered structure and low charge density. Crystalline materials, with inherently ordered porous structures, offer a promising alternative for overcoming these limitations.
View Article and Find Full Text PDFACS Appl Eng Mater
November 2024
Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria.
Organic electrochromic polymers hold great potential for integration into low-power flexible electrochromic displays (F-ECDs) due to their wide range of colors and simple processing. However, challenges such as inefficient charge transfer and degradation upon device integration hinder their practical applications. Herein, we report an innovative, general approach that utilizes template-induced supramolecular nanostructuring to engineer established electrochromic polymers, enhancing their performance and durability.
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