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Anti-Ulcerogenic Activity of the Marine-Pearl Derived Medicine Mukta Pishti in Rat Model of Pylorus Ligation-Induced Peptic Ulcer.
J Ethnopharmacol
January 2025
Drug Discovery and Development Division, Patanjali Research Foundation, Haridwar 249 405, Uttarakhand, India; Special Centre for Systems Medicine, Jawaharlal Nehru University, New Delhi 110 067, India. Electronic address:
Ethnopharmacological Relevance: Mukta Pishti (MKP) is a traditional Ayurvedic medicine described in classical textbook 'Rasatarangini' and synthesized from marine pearls following classical methodology. MKP is used as therapeutic medicine against hyperacidity, irritable bowel syndrome, and gastric ulcers.
Aim Of The Study: Here, we explored the therapeutic properties of MKP in alleviating peptic ulcer in Male Wistar rat model of pylorus ligation.
A Case of Robot-Assisted Pylorus-Preserving Pancreatoduodenectomy for Branch-Duct Intraductal Papillary Mucinous Neoplasms Complicated With an Annular Pancreas.
Asian J Endosc Surg
January 2025
Department of Hepato-Biliary-Pancreatic and Transplant Surgery, Mie University, Tsu, Mie, Japan.
Annular pancreas is a rare congenital anatomical anomaly, in which the pancreatic parenchyma surrounds the descending duodenum. Generally, annular pancreas is diagnosed on the basis of symptoms associated with complications of peptic ulcer, pancreatitis, cholelithiasis, and rarely, malignant tumors. Herein, we report an 84-year-old man for whom, during hospitalization for a urinary tract infection, pancreatic cystic lesions and an annular pancreas were noted incidentally on computed tomography.
View Article and Find Full Text PDFCircumferential Pyloric Ulcer Inducing Gastric Outlet Obstruction: A Report of a Rare Case.
Cureus
October 2024
Obstetrics and Gynaecology, Tameside General Hospital, Manchester, GBR.
We present a case of a 46-year-old female who presented to the hospital with significant abdominal distension, intractable vomiting, and pre-renal acute kidney injury (AKI) secondary to hypovolemia. Blood tests revealed global electrolyte derangements and a significant drop in estimated glomerular filtration rate (eGFR) from a baseline of over 90 to 6.7.
View Article and Find Full Text PDFPeptic Ulcer Disease: A Review.
JAMA
December 2024
University of Wisconsin School of Medicine and Public Health, Madison.
Importance: In the US, peptic ulcer disease affects 1% of the population and approximately 54 000 patients are admitted to the hospital annually for bleeding peptic ulcers.
Observations: Approximately 10% of patients presenting with upper abdominal pain in a primary care setting have a peptic ulcer as the cause of their symptoms. The principal causes of peptic ulcer disease are Helicobacter pylori infection, which affects approximately 42% of patients with peptic ulcer disease, and aspirin or nonsteroidal anti-inflammatory drug (NSAID) use, which are etiologic factors in approximately 36% of people with peptic ulcer disease.
[Chinese consensus on digestive tract reconstruction after proximal gastrectomy (2024 edition)].
Zhonghua Wei Chang Wai Ke Za Zhi
October 2024
The incidence of adenocarcinoma of the esophagogastric junction has been gradually increasing in recent years. Due to the smaller resection range, partial preservation of the function of stomach, high safety, better postoperative nutritional status, and lesser negative psychological impact on patients, the application of proximal gastrectomy has increased significantly. Proximal gastrectomy disrupts the normal anatomical structure of the esophagogastric junction, resulting in permanent loss of the anti-reflux function of the cardia.
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