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Extracranial and nonvaginal extragonadal malignant germ cell tumors: 12 cases at a Chinese institution over the last 38 years.
Arch Gynecol Obstet
January 2025
Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Purpose: To provide a comprehensive understanding and propose a strategy for the management of extragonadal malignant germ cell tumors (EMGCTs) arising from extracranial and nonvaginal sites.
Methods: We retrospectively reviewed the cases of 12 patients with EMGCTs arising from extracranial and nonvaginal sites treated in our center over the past 38 years. Data on clinicopathological characteristics, treatment modalities, and follow-up information were analyzed.
Current Trends in the Surgical Management of Yolk Sac Tumors.
Curr Oncol
November 2024
Department of Thoracic Surgery, 'Attikon' University Hospital of Athens, 12462 Athens, Greece.
Article Synopsis
- - Mediastinal yolk sac tumors (YST) are aggressive tumors that are often advanced and difficult to remove at the time of diagnosis, lacking a standardized treatment protocol due to their rarity.
- - The common treatment involves a combination of chemotherapy with cisplatin followed by extensive surgery, as tumors often invade nearby structures like the lungs and heart.
- - This review analyzes existing literature on surgical methods for treating YST, noting the limited information available and aiming to provide clinicians with a better understanding of the complex surgical approaches involved.
Primary mediastinal yolk sac tumor with multiple metastases on F-FDG PET/CT: A case report.
Asian J Surg
September 2024
Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050011, China; Hebei Provincial Key Laboratory of Tumor Microenvironment and Drug Resistance, Shijiazhuang, Hebei, 050011, China. Electronic address:
Maediastinal germ cell tumors: analysis using hospital-based cancer registry data in Japan.
Int J Clin Oncol
November 2024
Department of Urology, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Objectives: Mediastinal germ cell tumors are rare and few large-scale studies on mediastinal germ cell tumors are reported. We aimed to investigate the clinical characteristics and survival outcomes of patients with mediastinum germ cell tumors in Japan.
Methods: A hospital-based cancer registry data in Japan was used to identify and enroll patients diagnosed with mediastinal germ cell tumors in 2012-2013.
Subxiphoid robot-assisted complete resection for postchemotherapy primary mediastinal yolk sac tumour.
Multimed Man Cardiothorac Surg
August 2024
Department of General Thoracic Surgery, Gifu University Hospital, Gifu, Japan.
Article Synopsis
- The standard treatment for primary mediastinal yolk sac tumors usually includes neoadjuvant chemotherapy and surgery via traditional methods like sternotomy or thoracotomy.
- A 16-year-old patient underwent a less invasive, robot-assisted surgery to remove a large anterior mediastinal tumor, utilizing a da Vinci Xi system with CO2 insufflation.
- The procedure involved careful dissection, pericardiotomy, preservation of the right phrenic nerve, and reconstruction of the pericardial defect, highlighting a promising minimally invasive option for treating malignant mediastinal tumors.
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