Allele and genotype frequencies for six short tandem repeat (STR) loci were determined in a sample of 124 inhabitants from South Poland with commercial PCR-based typing kits. No deviations from Hardy-Weinberg expectations were found. The combined power of discrimination for the six loci was 0.9999982. There was no genotypic disequilibrium between the loci except for vWA and F13A01. The set of PCR loci was validated as useful for paternity testing and individual identification in the Polish population.
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http://dx.doi.org/10.1007/s004140050014 | DOI Listing |
Fa Yi Xue Za Zhi
August 2024
School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
Objectives: To establish the identification method of tumor tissue origin based on commonly used STR typing kits.
Methods: ForenSeq DNA Signature Prep kit was used to detect the typing of 27 autosomal STR loci in 55 paired tumor tissue samples (tumor tissue paired with normal tissue of the same individual) and 75 unrelated individual whole blood samples. The genotyping data of full sibling pairs and parent-child pairs of 55 tumor tissues were simulated.
Leg Med (Tokyo)
November 2024
Grupo de Investigación en Neurociencias, Facultad de Ciencias Médicas, Universidad Nacional Autónoma de Honduras, Edificio Ciencias de la Salud, Ciudad Universitaria, Blvd. Suyapa, Tegucigalpa, M.D.C., Honduras. Electronic address:
Ann Hum Genet
November 2024
Legal Medicine Research Center, Legal Medicine Organization of East Azerbaijan, Tabriz, Iran.
Leg Med (Tokyo)
July 2024
Forensic DNA Section, National Forensic Service Jeju Branch, 221, Cheomdan-ro, Jeju-si, Jeju-do 63309, Republic of Korea; Department of Forensic Medicine, Seoul National University College of Medicine, 103, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. Electronic address:
This study aimed to estimate A-STR mutation rates in 2,317 Korean parent-child trios by examining 20 Combined DNA Index System (CODIS) core loci (D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, CSF1PO, FGA, TH01, TPOX, vWA, D1S1656, D2S441, D2S1338, D10S1248, D12S391, D19S433, and D22S1045) and three non-CODIS loci (Penta E, Penta D, and SE33). Locus-specific mutation rate estimates varied from 0.00 to 8.
View Article and Find Full Text PDFForensic Sci Med Pathol
February 2024
Directorate of Forensic Science Laboratory, Mumbai, Maharashtra, India.
Short tandem repeat (STR) typing has been regularly used in paternity disputes and forensic human identification linked caseworks. Occasionally, forensic scientists come across aberrant allele patterns during STR typing because of mutations, genetic variations, and other abnormalities. The tri-allelic pattern of STR is rare, particularly, the case where this pattern exists at 4 loci.
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