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Previous surgery for lumbar spinal stenosis and association with amyloidosis and heart failure - A Danish nationwide study.
Amyloid
January 2025
Department of Cardiology, Copenhagen, Denmark.
Introduction: Cardiac Amyloidosis (CA) is characterised by amyloid fibril deposits causing heart failure (HF). Lumbar spinal stenosis (LSS) is recognised as a potential red flag for CA, but the association remains underexplored in large-scale studies.
Methods: This nationwide registry-based cohort study in Denmark included subjects ≥60 years with a history of LSS surgery.
Three-Staged Surgical Hybrid Treatment for an Extended Thoracoabdominal Aneurysm in a High-Risk Patient: A Case Report.
Cureus
December 2024
Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, JPN.
Thoracoabdominal aortic aneurysm (TAAA) repair remains one of the most challenging procedures and is associated with high mortality and complication rates. Careful consideration of the surgical strategy is essential, particularly in cases involving extensive replacement and high-risk patients. A 61-year-old man with a 55-mm TAAA was referred for surgical treatment.
View Article and Find Full Text PDFBackground: Although revascularization is first-line therapy for chronic limb-threatening ischemia (CLTI), there are no established treatments for patients in whom revascularization is not (or is a poor) option, including CLTI that has responded poorly to revascularization. This study verified the efficacy of the Rheocarna, a novel apheresis device, for no-option CLTI or poor-response CLTI after revascularization.
Methods And Results: This multicenter retrospective observational study analyzed 221 patients (221 limbs) with no- or poor-option CLTI (mean [±SD] age 71±10 years; males, 70.
ALTERNATIVE AUTOLOGOUS VEIN GRAFTS VERSUS SINGLE SEGMENT GREAT SAPHENOUS VEIN IN LOWER EXTREMITY BYPASS SURGERY - SINGLE-CENTER STUDY.
Ann Vasc Surg
January 2025
1(st) Department of Pathology, Faculty of Medicine, Masaryk University and St. Anne's University Hospital, Brno, Czech Republic.
Objectives: Studies comparing alternative autologous vein grafts (AAVG) to single-segment great saphenous vein (ssGSV) grafts report mixed results. The status of AAVG as first choice when ssGSV is unavailable is not unequivocal, based on current evidence. Our study compares results between AAVG and ssGSV in lower extremity bypass surgery.
View Article and Find Full Text PDFRegulatory T Cells for Stroke Recovery: A Promising Immune Therapeutic Strategy.
CNS Neurosci Ther
January 2025
Department of Research, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Background: Stroke remains a leading cause of mortality and disability among adults. Given the restricted therapeutic window for intravascular interventions and neuroprotection during the acute phase, there has been a growing focus on tissue repair and functional recovery in the subacute and chronic phases after stroke. The pro-inflammatory microglial polarization occurs in subacute and chronic phases after stroke and may represent therapeutic targets for stroke recovery.
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