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Speech, Language and Non-verbal Communication in CLN2 and CLN3 Batten Disease.
J Inherit Metab Dis
January 2025
Speech and Language, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
CLN2 and CLN3 diseases, the most common types of Batten disease (also known as neuronal ceroid lipofuscinosis), are childhood dementias associated with progressive loss of speech, language and feeding skills. Here we delineate speech, language, non-verbal communication and feeding phenotypes in 33 individuals (19 females) with a median age of 9.5 years (range 3-28 years); 16 had CLN2 and 17 CLN3 disease; 8/15 (53%) participants with CLN2 and 8/17 (47%) participants with CLN3 disease had speech and language impairments prior to genetic diagnosis.
View Article and Find Full Text PDFEffects of eccentric resistance training after stroke on body function, activities of daily living and cognitive function: A review.
Sports Med Health Sci
March 2025
FPCEE-Blanquerna, Ramon Llull University, Barcelona, Spain.
Impairments on body function, activities of daily living (ADL) and cognition are common after stroke. Eccentric resistance training (ERT) may be implemented to improve them. The primary objectives were to evaluate whether ERT improves body function, ADL and cognition after stroke.
View Article and Find Full Text PDFThe Effects of Nocturnal Hypoxemia on Cognitive Performance in Andean Highlanders.
High Alt Med Biol
December 2024
Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, Department of Medicine, University of California, San Diego, California, USA.
Many Andean highlanders exposed to chronic hypoxemia are susceptible to excessive erythrocytosis (EE) and chronic mountain sickness (CMS). Nocturnal hypoxemia is more marked than diurnal hypoxemia and includes sustained and intermittent components. The potential for cognitive impairments related to nocturnal hypoxemia in this population has not been extensively studied, but improved understanding may provide opportunities for the prevention of long-term effects of EE and CMS.
View Article and Find Full Text PDFSocial isolation and social cognition: A cross-sectional analysis.
J Alzheimers Dis
November 2024
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The impact of social isolation on social cognition is not entirely clear.
Objective: The aim of the study is to investigate the association between social isolation and social cognition.
Methods: In a population-based sample of 83 individuals aged 50+ years without dementia, we assessed the relationship between social isolation (measured by the Lubben Social Network Scale - LSNS-6) and performance on emotional recognition (measured by the Emotion Recognition Task (ERT)) and on Theory of Mind (ToM) abilities (measured by the Reading the Mind in the Eyes Test (RMET)), two core aspects of social cognition.
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