AI Article Synopsis

  • The post-coital test (PCT) evaluates cervical mucus and sperm movement in the female reproductive tract, providing insight into fertility.
  • A negative PCT result does not rule out pregnancy potential, highlighting its limitations.
  • Higher numbers of motile sperm observed in the mucus correlate with increased pregnancy rates, suggesting a filtering mechanism that may exclude abnormal sperm, while "shaking" behavior indicates a possible immune response against male sperm.

Article Abstract

The choice of optimal time, the technique and limitations of the post-coital test (PCT) have been described. They are of important significance for getting reliable information both concerning the cervical mucus, quality and migration of spermatozoa in female genital tract. It has been stressed that a negative PCT does not necessary exclude pregnancy. There are shown data for prognostic value of the PCT. The observation of more than 20 motility spermatozoa per HPF and higher frequency of pregnancy is common finding in comparison to low motility and number of spermatozoa in cervical mucus. The data support the hypothesis of "filtering" mechanism, excluding entrance of abnormal spermatozoa. Observing "shaking" phenomenon directs to searching immunological factor (local or systemic) against male gametes.

Download full-text PDF

Source

Publication Analysis

Top Keywords

cervical mucus
8
[the postcoital
4
postcoital test
4
test clinico-laboratory
4
clinico-laboratory observations]
4
observations] choice
4
choice optimal
4
optimal time
4
time technique
4
technique limitations
4

Similar Publications

Mucus plays an integral role for the barrier function of many epithelial tissues. In the human airways, mucus is constantly secreted to capture inhaled microbes and pollutants and cleared away through concerted ciliary motion. Many important respiratory diseases exhibit altered mucus flowability and impaired clearance, contributing to respiratory distress and increased risk of infections.

View Article and Find Full Text PDF

Introduction: Invasive Stratified Mucin-producing Carcinoma (ISMC) of the cervix is a newly named cervical adenocarcinoma associated with Human Papilloma virus (HPV). Due to its relative rarity, clinical data, pathological features, and molecular characteristics of ISMC are still under exploration. This study aims to retrospectively analyze the clinical data and pathological features of ISMC patients, summarizing the clinical and pathological morphological characteristics of ISMC.

View Article and Find Full Text PDF

Engrailed-2 (EN2) protein in cervical mucus: a novel biomarker for endometrial carcinoma.

Clin Transl Oncol

November 2024

Institute of Cardiovascular Sciences, Peking University Health Science Center, No. 38 Xueyuan Road, Handian District, Beijing, China.

Objective: This study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer.

Materials And Methods: This study included 133 patients who were treated at Beijing Obstetrics and Gynecology Hospital. According to the pathological results of hysteroscopy endometrial biopsy, the patients were divided into endometrial cancer group (n = 55), endometrial atypical hyperplasia group (n = 16), benign lesion group (n = 28), and control group (n = 34).

View Article and Find Full Text PDF

A multi-class support vector machine classification model based on 14 microRNAs for forensic body fluid identification.

Forensic Sci Int Genet

February 2025

Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China. Electronic address:

Article Synopsis
  • MicroRNAs (miRNAs) show promise for identifying body fluids in forensics due to their stability and unique expression patterns, but their relative expression makes identification challenging.
  • The study validated reference genes and selected a combination of miRNAs to create a multi-class support vector machine (MSVM) model that predicts body fluid origins with high accuracy, even for aged or mixed samples.
  • Further validation across different labs is needed before implementing miRNAs in routine forensic practice.
View Article and Find Full Text PDF

Objective: The objective was to develop a manually operatable, non-electric device to measure salivary spinnbarkeit for research, clinical and educational purposes.

Materials And Methods: A newly developed device, named the Kamranmeter, was built and evaluated in a pilot study, comparing the spinnbarkeit of unstimulated and chew-stimulated saliva samples from healthy volunteers. The Neva Meter, which operates on electrical resistance, was used as a reference standard.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!