Humoral and cellular immunity were studied in 34, 59 and 21 patients with mild, moderate and severe tropical malaria in the course of the disease. It was found that immunological indices in tropical malaria change with the disease severity. Some immunological indices may be indicative of the infection severity, outcome and prognosis of the disease and contribute to more effective chemotherapy and immunocorrection.
Download full-text PDF |
Source |
---|
Med Vet Entomol
January 2025
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Mass ivermectin (IVM) treatment of livestock (MITL) is under consideration as a malaria control tool as IVM-treated livestock are lethal to blood-feeding Anopheles mosquitoes. MITL is routinely used as a prophylaxis in livestock to reduce the burden and transmission of helminth infections. Recently, there has been a shift in the veterinary IVM market in Southeast Asia wherein nearly all standard IVM formulations are now co-formulated with clorsulon (CLO).
View Article and Find Full Text PDFLancet Reg Health Am
February 2025
Caribbean Public Health Agency, Port of Spain, Trinidad and Tobago.
Iran J Pharm Res
September 2024
Department of Parasitology and Mycology, Skin Diseases and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Malaria parasites have gradually developed resistance to commonly used antimalarial drugs. For decades, chloroquine was the most widely used drug to eradicate malaria. However, with the spread of chloroquine resistance, many countries have adopted combination therapies that utilize two drugs acting synergistically instead of monotherapy.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
UMR261 MERIT, Université Paris Cité, IRD, Paris, France.
Background: Malaria infections in pregnancy are a major cause of maternal morbidity and neonatal mortality in sub-Saharan Africa. A high proportion of these infections are submicroscopic, which are usually asymptomatic and therefore untreated during pregnancy. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) aims to prevent and treat all potential infections whether submicroscopic or not.
View Article and Find Full Text PDFLancet Infect Dis
January 2025
Ministry of Health, Kampala, Uganda.
Background: Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine combined with amodiaquine (SPAQ) effectively protects eligible children from malaria in areas of high and seasonal transmission. However, concerns about parasite resistance to sulfadoxine-pyrimethamine in East and Southern Africa necessitate evaluating alternative drug regimens. This study assessed the effectiveness of SPAQ and dihydroartemisinin-piperaquine for SMC in Uganda.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!