In 30--60 minutes following their administration sodium oxybutyrate in a dose of 100 mg/kg, mexamine in a dose of 2.5 and 5 mg/kg and also gutimine in doses of 25,50 and 100 mg/kg under conditions of hypoxic hypoxia corresponding to an altitude of 10000 m produce a marked antihypoxic effect. A combination of sodium oxybutyrate in the above dose, of mexamine in amounts of 1,2.5 and 5 mg/kg and also of gutimine in doses of 25,50 and 100 mg/kg permit it in some cases to achieve potentiation of antihypoxic effects of the drugs.
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