AI Article Synopsis
- Tuberculosis is a rare but serious infection that can occur after stem cell transplants, as highlighted by a case study.
- A patient developed a brain mass three months after being diagnosed with pulmonary tuberculosis, despite undergoing triple therapy and having chronic graft-versus-host disease (GVHD).
- After the brain lesion was surgically removed and treatment continued, the patient initially recovered but later died from a separate infection, emphasizing the need for awareness of mycobacterial infections in transplant recipients with chronic GVHD.
Article Abstract
Tuberculosis is an uncommon infectious complication after stem cell transplantation. We report a patient who presented with a brain mass, 3 months after pulmonary tuberculosis had been diagnosed and while he was receiving triple antituberculous therapy. He had extensive chronic GVHD. The diagnosis was made after biopsy of the lesion. The cerebral mass was excised, antituberculous treatment was maintained and the patient made a complete neurologic recovery. Six months later, he died of gram-negative septic shock. Mycobacterial infections should be considered in allograft recipients with chronic GVHD and solid lesions in the brain. Bone Marrow Transplantation (2000) 25, 567-569.
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| http://dx.doi.org/10.1038/sj.bmt.1702163 | DOI Listing |
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