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Bioinformatics identification of characteristic genes of cervical cancer via an artificial neural network.
Chin Clin Oncol
February 2024
Department of Obstetrics and Gynecology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Background: Artificial neural networks (ANNs) have been extensively used in the field of medicine. The present hypothesis-free study sought to use an ANN to identify the characteristic genes of cervical cancer (CC).
Methods: RNA sequencing profiles were obtained from the GSE7410, GSE9750, GSE63514, and GSE52903 datasets.
Liver Regeneration-Related Genes of Nontumor Liver Tissues Predict the Prognosis of Patients with Hepatocellular Carcinoma.
J Hepatocell Carcinoma
December 2023
Department of Hepatobiliary Surgery, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, People's Republic of China.
Background: Hepatocellular carcinoma (HCC) is one of the most serious malignant tumors threatening human life with a high mortality rate. The liver regenerative capacity after hepatectomy in early-stage HCC patients is influenced by various factors, including surgical methods and energy metabolism. This study aims to provide a prognostic model based on genes related to liver regeneration that can predict the prognosis of non-tumor tissues in HCC patients.
View Article and Find Full Text PDFAdult Refsum Disease in Puerto Rico: A Case Report.
Cureus
September 2023
Ophthalmology, University of Puerto Rico, Medical Sciences Campus, San Juan, PRI.
Article Synopsis
- Adult Refsum Disease (ARD) patients typically exhibit symptoms like night blindness, smell loss, hearing impairment, and balance issues, along with physical traits such as short metacarpals and cardiac arrhythmias.
- This case study highlights a patient with ARD showing specific symptoms, including retinitis pigmentosa and reduced macular thickness, indicating progressive eye degeneration.
- The report emphasizes the need for better diagnostic criteria and mentions that this is the first documented case of ARD in Puerto Rico.
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