AI Article Synopsis
- - Ferula communis, a plant from the Mediterranean, has two varieties in Morocco, with one (genuina) known for producing a medicinal resin called fessoukh, used in traditional medicine.
- - The review covers the plant's uses in ethnobotany, detailing its medicinal applications and the young stems' edible qualities, as well as the intoxication risks primarily leading to hemorrhage due to blood coagulation issues.
- - It highlights the anticoagulant properties of 4-hydroxycoumarins found in the plant and discusses how vitamin K1 can aid in treating poisoning from Ferula communis.
Article Abstract
Ferula communis is an ombelliferous plant of the Mediterranean regions. It is represented in Morocco by two varieties: brevifolia and genuina. The later is very rich in a soap or resinous gum. This product, collected from the roots, is largely used in traditional medicine. It is know as fessoukh in Morocco and other Arab countries. This plant is also well known for its toxicity and its anticoagulant activity. In the present review, are discussed: (1) the ethnobotany of the plant, especially medicinal uses of fessoukh in traditional medicine as well as alimentary use of young stems as legumes; (2) clinical and biochemical data of intoxication by this plant, which are dominated by haemorrhage as a consequence of blood coagulation disturbance; (3) 4-hydroxycoumarins isolated from Ferula communis L. and their anticoagulant activity; (4) the role of vitamin K1 in the treatment of poisoning by this plant.
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