A soft tissue injury can lead to the formation of a pseudocyst in the subcutaneous adipose tissue, due to a seroma, haematoma or fat necrosis. These cysts were first described in 1853 by the French physician Morel-Lavallée. He observed the phenomenon in the lower limb in women after a tangential trauma with separation of the fatty layers. A similar condition can occur following surgery of the abdomen, when performing liposuction and subcutaneous dissection with a large dead space. In this report we present two cases with large pseudocysts in the abdominal wall, which were seen in long term follow-up after an abdominoplasty performed elsewhere. The pathogenesis, the treatment and the literature are discussed.
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http://dx.doi.org/10.1054/bjps.1999.3154 | DOI Listing |
Acta Parasitol
January 2025
Department of Molecular Biology and Genetics, Ordu University, Ordu, Turkey.
Pancreatology
December 2024
Department of Surgery, University of California Los Angeles, Los Angeles, CA, USA. Electronic address:
Background/objectives: Genetic variants in PRSS1 encoding human cationic trypsinogen are associated with hereditary pancreatitis. The clinically frequent variants exert their pathogenic effect by increasing intrapancreatic trypsin activity, while a distinct subset of variants causes disease via mutation-induced trypsinogen misfolding and endoplasmic reticulum (ER) stress. Here, we report a novel misfolding PRSS1 variant.
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December 2024
Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary; Translational Pancreatology Research Group, Interdisciplinary Centre of Excellence for Research Development and Innovation, University of Szeged, Szeged, Hungary. Electronic address:
Background: Pancreatic cancer (PC) is a leading cause of cancer mortality, often diagnosed at advanced stages. Acute pancreatitis (AP), particularly idiopathic cases, may serve as an early indicator of PC.
Objective: This multicenter cohort study investigated the incidence of PC before and after an AP episode, focusing on idiopathic AP and the role of pseudocysts as potential early markers for PC development.
BMJ Case Rep
December 2024
Department of Pediatrics, Lithuanian University of Health Sciences Hospital Kauno klinikos, Kaunas, Lithuania.
Acute pancreatitis in children is a rare condition; however, the incidence of this acute condition has been increasing over the past few decades. In most cases, acute pancreatitis does not cause severe complications in children, but in some cases, it can be complicated by fluid accumulation, fistulas and vascular pathologies, but the most common complication remains the formation of pseudocysts. This article describes the clinical case of a 11-year-old girl from Lithuania, which effectively illustrates a rare condition in children-acute pancreatitis and its developed complication-the formation of a pancreatic pseudocyst.
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