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Ann Endocrinol (Paris)

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Université Paris-Saclay, Inserm, Endocrine Physiology and Physiopathology, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction and Centre de Référence des Maladies Rares de l'Hypophyse HYPO, F-94270 Le Kremlin-Bicêtre, France. Electronic address:

Primary hyperparathyroidism is rare in children. A germline mutation is identified in half of all children with primary hyperparathyroidism (70% of newborns and infants, and 40% of children and adolescents). The clinical manifestations of primary hyperparathyroidism in children are highly variable (often absent in newborns, rather severe and symptomatic in children and adolescents) and depend on the genetic cause, as well as the severity, rapidity of onset and duration of hypercalcemia.

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Maintaining an optimal indoor thermal environment is crucial for enhancing the welfare and productivity of livestock in intensive breeding farms. This paper investigated the application of a combined geothermal heat pump with a precision air supply (GHP-PAS) system for cooling dairy cows on a dairy farm. The effectiveness of the GHP-PAS system in mitigating heat stress in lactating dairy cattle, along with its energy performance and local cooling efficiency in the free stalls were evaluated.

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