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Syndromic fibrous dysplasia of the proximal femur.
BMJ Case Rep
January 2025
General Surgery, MS Ramaiah Medical College, Bangalore, Karnataka, India.
A woman in her 50s presented with a 1-year history of left hip pain that increased over the past 2 weeks. The pain began following a low-energy fall. During the 1-year period, she had multiple lesions in the thigh and gluteal region, which were surgically excised.
View Article and Find Full Text PDFIntramuscular hemangioma capillary type with HRAS mutation: Expanding the molecular genetic spectrum with an emphasis on overlap with arteriovenous malformations and distinct from infantile hemangioma.
Hum Pathol
November 2024
Department of Pathology, Henan Provincial People's Hospital, the People's Hospital of Zhengzhou University, Zhengzhou, China. Electronic address:
Article Synopsis
- Intramuscular hemangioma capillary type (IHCT) is a rare, fast-flow vascular lesion characterized by painless masses that commonly affect young adults and can involve various body locations, including the trunk and extremities.
- The study analyzed ten surgically treated IHCT cases from a pathology database and identified significant histopathological features, such as capillary-type vessels, and detected various somatic mutations, particularly in the MAP2K1 and KRAS genes.
- The findings suggest that IHCT shares genetic and hemodynamic similarities with arteriovenous malformations (AVMs), indicating potential new genetic targets for treatment development.
Intramuscular Venous Malformation Associated with Muscle Herniation of the Left Masseter Muscle in a 12-Year-Old Boy.
Am J Case Rep
September 2024
Department of Radiology, Faculty of Medicine, Taibah University, Medina, Saudi Arabia.
BACKGROUND Muscle hernias are an uncommon condition typically found in the extremities; masseter muscle hernia is even rarer. However, it is important for clinicians and radiologists to be aware of this possibility. Intramuscular venous malformation (IMVM) is also uncommon and mostly found in the head, neck, and extremities.
View Article and Find Full Text PDFConcomitant Botulinum Toxin Injections for Neurogenic Detrusor Overactivity and Spasticity-A Retrospective Analysis of Practice and Safety.
Toxins (Basel)
May 2024
Spinal Unit, Department of Physical and Rehabilitation Medicine, Raymond Poincaré Teaching Hospital, APHP Paris Saclay, 92380 Garches, France.
Article Synopsis
- This study explored the safety and effectiveness of simultaneous botulinum toxin injections (BTIs) used to treat both spasticity and neurogenic detrusor overactivity incontinence (NDOI) in patients with spinal cord injuries and multiple sclerosis.
- Researchers identified 72 patients over five years who received both types of injections within one month, revealing a majority were male (69%) and mostly had spinal cord injuries (76%).
- The analysis showed 95% of injections occurred within 72 hours, with very few adverse symptoms reported, suggesting that simultaneous BTIs are safe when adhering to established dosage guidelines.
Erosive hand osteoarthritis and sarcopenia: data from Osteoarthritis Initiative cohort.
Ann Rheum Dis
May 2024
Russell H. Morgan Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Objectives: There is no evidence linking specific osteoarthritis (OA) types, such as erosive hand OA (EHOA), with distant generalised changes in muscle composition (sarcopenia), which can potentially be modified. This study pioneers the exploration of the association between EHOA and sarcopenia, both of which are predominantly observed in the older adults.
Methods: Using the Osteoarthritis Initiative cohort, we selected hand OA (modified Kellgren and Lawrence (grade ≥2 in ≥1 hand joint) participants with radiographic central erosions in ≥1 joints (EHOA group) and propensity score-matched hand OA participants with no erosion (non-EHOA group).
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