[Pernicious anemia: the African experience (3 cases reports)].

Sante

Centre Marc-Sankale, Clinique médicale II, Service de médecine interne, BP 5062, Fann, Dakar, Sénégal.

Published: March 2000

AI Article Synopsis

  • Three women in Africa were diagnosed with pernicious anemia, showing macrocytic anemia and megaloblasts in their bone marrow.
  • Each patient exhibited neurological symptoms related to combined sclerosis, supporting the anemia diagnosis.
  • Successful treatment involved vitamin injections, highlighting that pernicious anemia may be more common in Africa than previously recognized.

Article Abstract

We report three cases of pernicious anemia diagnosed in women in Africa. All three women had macrocytic anemia with megaloblasts evident on medullogram. The patients had neurological signs of combined sclerosis and the presence of megaloblasts confirmed the diagnosis of pernicious anemia. All were successfully treated parenterally with vitamins. This disease seems to be underdiagnosed in Africa given the number of cases reported in previous studies.

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