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Dual Biological Effects and Mechanisms of Gut Microbiota in Breast Cancer: A Review.
Curr Pharm Biotechnol
January 2025
Department of Pharmacology, College of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia, China.
Breast cancer (BC) is a common malignant tumor. BC is serious and has a high mortality rate. The incidence of BC has increased in recent years.
View Article and Find Full Text PDFA roadmap from the bond strength to the grain-boundary energies and macro strength of metals.
Nat Commun
January 2025
Key Laboratory of Automobile Materials, Ministry of Education, Department of Materials Science and Engineering, Jilin University, 130022, Changchun, China.
Correlating the bond strength with the macro strength of metals is crucial for understanding mechanical properties and designing multi-principal-element alloys (MPEAs). Motivated by the role of grain boundaries in the strength of metals, we introduce a predictive model to determine the grain-boundary energies and strength of metals from the cohesive energy and atomic radius. This scheme originates from the d-band characteristics and broken-bond spirit of tight-binding models, and demonstrates that the repulsive/attractive effects play different roles in the variation of bond strength for different metals.
View Article and Find Full Text PDFAdaptation of Archaeal Communities to Summer Hypoxia in the Sediment of Bohai Sea.
Ecol Evol
January 2025
Tianjin Key Laboratory of Animal and Plant Resistance, Tianjin Key Laboratory of Conservation and Utilization of Animal Diversity, College of Life Science Tianjin Normal University Tianjin China.
Understanding the adaptation of archaea to hypoxia is essential for deciphering the functions and mechanisms of microbes when suffering environmental changes. However, the dynamics and responses of archaea to the sedimentary hypoxia in Bohai Sea are still unclear. In this study, the diversity, composition, and distribution of archaeal community in sediment along an inshore-offshore transect across the oxygen-depleted area in the Bohai Sea were investigated in June, July, and August of 2021 by employing high-throughput sequencing of 16S rRNA gene.
View Article and Find Full Text PDFEffect of fructooligosaccharides in full-hydrated lactic acid bacteria membrane models during thermal stress: A molecular simulation study.
Food Res Int
January 2025
University of Coimbra, CERES, Department of Chemical Engineering, Rua Sílvio de Lima, Coimbra 3030-790, Portugal. Electronic address:
Fructooligosaccharides (FOS) are a promising choice for cryoprotection of lactic acid bacteria (LAB). However, the mechanism by which this protection takes place is not well understood. Molecular simulation is a key tool for gathering insights into complex physicochemical problems like this.
View Article and Find Full Text PDFRegional antimicrobial resistance gene flow among the One Health sectors in China.
Microbiome
January 2025
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Background: Antimicrobial resistance poses a significant threat to global health, with its spread intricately linked across human, animal, and environmental sectors. Revealing the antimicrobial resistance gene (ARG) flow among the One Health sectors is essential for better control of antimicrobial resistance.
Results: In this study, we investigated regional ARG transmission among humans, food, and the environment in Dengfeng, Henan Province, China by combining large-scale metagenomic sequencing with culturing of resistant bacterial isolates in 592 samples.
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