Two antifungal triterpenoid glycosides, hyalodendrosides A and B (1 and 2), were isolated from a solid matrix fermentation of a lignicolous hyphomycete, Hyalodendron sp. Their structures were determined based upon extensive examination of spectral parameters, particularly NMR and MS data. Both compounds have beta-linked glucose moieties. Compounds 1 and 2 show weak to moderate antifungal activity against some clinically relevant fungi.

Download full-text PDF

Source
http://dx.doi.org/10.1021/np9903898DOI Listing

Publication Analysis

Top Keywords

antifungal triterpenoid
8
triterpenoid glycosides
8
lignicolous hyphomycete
8
hyphomycete hyalodendron
8
hyalodendrosides antifungal
4
glycosides lignicolous
4
hyalodendron species
4
species antifungal
4
glycosides hyalodendrosides
4
hyalodendrosides isolated
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!