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Recalcitrant Pustular Dermatosis Successfully Treated With Prolonged Isotretinoin Therapy.
Cureus
November 2024
Dermatology, Imperial Dermatology, Hollywood, USA.
Isotretinoin (13-cis-retinoic acid) is a well-established systemic treatment for moderate to severe acne vulgaris, renowned for its ability to target multiple contributors to acne pathogenesis. However, its therapeutic potential extends beyond conventional acne management. This case report highlights its efficacy in treating recalcitrant pustular dermatosis, a condition that proved resistant to standard therapies and posed significant diagnostic challenges.
View Article and Find Full Text PDFHistopathologic Comparisons of Discoid Lupus Erythematosus and Folliculotropic Mycosis Fungoides in a Series of 43 Cases.
J Cutan Pathol
February 2025
Oakland University William Beaumont School of Medicine, Rochester Hills, Michigan, USA.
Background: Folliculotropic mycosis fungoides (FMF) is a rare cutaneous malignancy that can be mistaken for inflammatory diseases, such as discoid lupus erythematosus (DLE), due to the variability of histopathological findings.
Methods: This study aims to provide dermatopathologists with evidence-based histopathologic criteria to distinguish DLE from FMF by reporting overlapping and distinguishing microscopic features. Forty-three biopsies from patients with a confirmed diagnosis of DLE or FMF were graded for the presence or absence of 18 histopathologic features.
Compound Follicles in Folliculitis Decalvans Do Not Contain Vellus and Retained Telogen Follicles-A Pilot Histopathologic Series on Polytrichia.
J Cutan Pathol
January 2025
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Article Synopsis
- - Polytrichia is a common observation in folliculitis decalvans (FD), linked to compound follicular structures (CFS) that involve multiple hair follicles sharing a single opening and surrounded by fibrous tissue.
- - A study analyzed 10 scalp biopsy samples from patients with early-stage FD, focusing on the types and quantities of follicles within these CFS.
- - The findings revealed that of 205 follicles examined, 156 were terminal follicles, primarily in the anagen phase, providing insights into the pathology of FD.
Mepolizumab-responsive recurrent eosinophilic eruption without peripheral eosinophilia.
JAAD Case Rep
November 2024
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Novel association of eosinophilic pustular folliculitis with systemic lupus erythematosus: A case report.
JAAD Case Rep
October 2024
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
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