Nowadays there is a transition from the automation of some tasks to a complex computerization of medicogenetic service in Russia on the basis of the Federal genetic register. The system is multifunctional and ensures the keeping all medical records. It is realized through the corporate global network. The operations performed will also provide an intellectual support of medical geneticists' decisions.
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Eur J Drug Metab Pharmacokinet
January 2025
School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Background And Objective: A gonadotropin-releasing hormone (GnRH) agonist such as leuprolide is widely used to achieve sustained suppression of testosterone levels, which play a critical role in the treatment of prostate cancer. Recent advances in drug delivery systems have led to the development of long-acting depot formulations, such as the 6-month intramuscular (IM) leuprolide formulation, which aim to simplify dosing and improve convenience for both patients and healthcare providers. Exploring extended dosing intervals for such formulations represents a promising approach to further optimize treatment regimens, potentially balancing efficacy with patient-centered care.
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January 2025
Department of Distributed Systems and Informatic Devices, Gliwice, Poland.
The advancement of IT systems necessitates efficient communication methods essential across various sectors, from streaming platforms to cloud-based solutions and Industry 4.0 applications. Enhancing Quality of Service (QoS) in computer networks by focusing on bandwidth and communication delay is critical.
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January 2025
School of Electronics and Information Engineering, University of Science and Technology Liaoning, Anshan, 114051, China.
Collective behavior in biological systems emerges from local interactions among individuals, enabling groups to adapt to dynamic environments. Traditional modeling approaches, such as bottom-up and top-down models, have limitations in accurately representing these complex interactions. We propose a novel potential field mechanism that integrates local interactions and environmental influences to explain collective behavior.
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January 2025
Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.
A key question about social media use is whether it constitutes an addiction. A possible frame of reference to investigate this question is the Incentive Sensitizations Theory (IST), as it provides a solid empirical background to understand the motivational and hedonic aspects of problematic behaviors. A central assumption of IST that addiction-related cues play a pivotal role in addictive behaviors has remained relatively understudied in the context of social media use.
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January 2025
Computer Science and Engineering Department, Universidad Carlos III de Madrid, Av. Universidad, 30, Leganés, 28911, Madrid, Spain.
This article describes a dataset on nut allergy extracted from Spanish clinical records provided by the Hospital Universitario Fundación de Alcorcón (HUFA) in Madrid, Spain, in collaboration with its Allergology Unit and Information Systems and Technologies Department. There are few publicly available clinical texts in Spanish and having more is essential as a valuable resource to train and test information extraction systems. In total, 828 clinical notes in Spanish were employed and several experts participated in the annotation process by categorizing the annotated entities into medical semantic groups related to allergies.
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