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Case report: successful treatment of primary intradural extramedullary extraskeletal Ewing sarcoma in adult patient with intralesional surgery, chemotherapy, and proton beam therapy of the cerebrospinal axis.
Ther Adv Med Oncol
November 2024
Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Skłodowska-Curie National Research Institute of Oncology, Roentgena 5, Warsaw 02-781, Poland.
Ewing sarcoma is a rare malignant neoplasm that primarily affects bone in children. Extraskeletal location is less common, while intradural extramedullary Ewing sarcoma (IEES) in adults is a casuistic phenomenon. Due to its rarity, a standardized treatment strategy for IEES has not been established.
View Article and Find Full Text PDFA rare case of multifocal craniospinal leptomeningeal melanocytoma: A case report and scoping review.
Brain Spine
March 2024
Department of Neurosurgery, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Introduction: Leptomeningeal melanocytomas are rare tumours originating from neural crest derived melanocytes. They are usually solitary and presentation with multifocal meningeal melanocytoma is very rare and indicative of potentially more aggressive behaviour. This case report and scoping review sought to evaluate the presentation, and key radiological features that can help differentiate multifocal meningeal melanocytoma from other differentials and provide a discussion of the key management and prognostic points once these tumours are diagnosed.
View Article and Find Full Text PDFClinical diagnostic and radiographic features of primary spinal atypical teratoid rhabdoid tumors tumor in a pediatric patient: A case report and review of the literature.
J Cent Nerv Syst Dis
October 2023
Department of Neurosurgery, University of Iowa Hospital and Clinics, Iowa City, IA, USA.
Atypical teratoid rhabdoid tumors (ATRTs) are rare embryonal tumors comprising 1-2% of all pediatric CNS neoplasms. Spinal ATRTs are even more uncommon, accounting for 2% of all reported ATRT cases. Despite their rarity, ATRTs affect young children disproportionately and are characterized by a high malignant potential due to a heterogeneous cellular composition and inactivating mutations in the (90%) and (10%) genes.
View Article and Find Full Text PDFSpinal atypical teratoid rhabdoid tumor-narrative review and report of a rare case managed with multimodality approach.
Childs Nerv Syst
August 2023
Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Background: Spinal atypical teratoid rhabdoid tumor (AT/RT) is an extremely rare tumor and represents less than 2% of all AT/RTs.
Methods: Available medical literature on spinal AT/RT in English was retrieved from PubMed and comprehensively reviewed. Clinical presentation, diagnosis, management, prognosis, and outcome in patients with spinal AT/RT have been elucidated by citing a case of extradural AT/RT of the cervicodorsal spine.
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