Objectives: To investigate the consequences of rally driving on lumbar degenerative changes.
Background: Vehicular driving is suspected to accelerate disc degeneration through whole-body vibration, leading to back problems. However, in an earlier well-controlled study of lumbar MRI findings in monozygotic twins, significant effects of lifetime driving on disc degeneration were not demonstrated. Another study of machine operators found only long-term exposure to vibration on unsprung seats led to a reduction in disc height.
Design: Case-control study comparing rally drivers with population sample.
Methods: Eighteen top rally drivers and co-drivers, mean age 43 yrs (SD, 10), volunteered for the study. The subjects were interviewed and imaged with a MR scanning and lumbar images were analyzed for degenerative findings using a standard scoring protocol previously published. The reference group was composed of 14 men, mean age 55 yrs (SD, 10), selected from a population sample.
Results: Overall results showed no significant differences in lumbar degenerative findings as assessed from MR images between the rally drivers and the reference group; age-adjusted differences were not statistically significant for disc heights, bulges, herniations, end-plate irregularities, or osteophytes.
Conclusion: Even extreme vehicular vibration as experienced in rally driving does not appear to have significant effects on disc generation.
Relevance: The study results do not support driving, and its associated whole body vibration, as a significant cause of disc degeneration and question the theory that the higher incidence of back pain among drivers is due to accelerated disc degeneration. Other driving-related factors, such as postural stress, may deserve more attention.
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http://dx.doi.org/10.1016/s0268-0033(99)00047-9 | DOI Listing |
Objective: Aim: To investigate the peculiarities of deviations of preoperative values of biochemical markers of inflammation in the blood serum of patients with degenerative diseases of the lumbar spine after transpedicular fixation, with a complicated postoperative course to predict the development of various postoperative complications.
Patients And Methods: Materials and Methods: The content of glycoproteins (GP), sialic acids (SA), C-reactive protein (CRP), seroglicoids (SG), haptoglobin (HG), Veltman`s test (VT) were investigated. The results are comparable by the Student-Fisher method.
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Organoid Research Center, Institute of Translational Medicine, Shanghai University, Shanghai, China.
The skeletal system, composed of bones, muscles, joints, ligaments, and tendons, serves as the foundation for maintaining human posture, mobility, and overall biomechanical functionality. However, with ageing, chronic overuse, and acute injuries, conditions such as osteoarthritis, intervertebral disc degeneration, muscle atrophy, and ligament or tendon tears have become increasingly prevalent and pose serious clinical challenges. These disorders not only result in pain, functional loss, and a marked reduction in patients' quality of life but also impose substantial social and economic burdens.
View Article and Find Full Text PDFInflamm Res
January 2025
Department of Orthopedics and Traumatology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China.
Background: One of the etiologic components of degenerative spinal illnesses is intervertebral disc degeneration (IVDD), and the accompanying lower back pain is progressively turning into a significant public health problem. Important pathologic characteristics of IVDD include inflammation and acidic microenvironment, albeit it is unclear how these factors contribute to the disease.
Purpose: To clarify the functions of inflammation and the acidic environment in IVDD, identify the critical connections facilitating glycolytic crosstalk and nucleus pulposus cells (NPCs) pyroptosis, and offer novel approaches to IVDD prevention and therapy.
Acta Bioeng Biomech
September 2024
Xinjiang University, China.
: The purpose of this study was to investigate dynamic responses of Lenke1B+ spines of adolescent scoliosis patients to different frequencies. : Modal analysis, harmonic response analysis and transient dynamics of a full spine model inverted by the finite element method using Abaqus. : The first-order axial resonance frequency of 4.
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January 2025
Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, China.
Unlabelled: Intervertebral disc degeneration is the leading cause of low back pain, imposing significant burdens on patients, societies, and economies. Advancements in regenerative medicine have spotlighted extracellular vesicles as promising nanoparticles for intervertebral disc degeneration treatment. Extracellular vesicles retain the potential of cell therapy and serve as carriers to deliver their cargo to target cells, thereby regulating cell activity.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!