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Communication and diffusion of the 2022 French Urolithiasis Guidelines (CLAFU) : lessons from a national audit.
Fr J Urol
March 2025
GRC n°20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France; Department of Urology, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France; Department of Urology, La Croix du Sud Clinic-RGDS, UroSud, 52 bis Chemin de Ribaute, Boite 301, 31130 Quint Fonsegrives, France; PIMM, UMR 8006 CNRS-Arts et Métiers ParisTech, 151 bd de l'Hôpital, F-75013 Paris, France; Progressive Endourological Association for Research and Leading Solutions (PEARLS group), France. Electronic address:
Objectives: The French 2022 Urolithiasis(CLAFU) Guidelineswere recently released. We aimed to evaluate the impact and diffusion of these CLAFU guidelines among the French Urologists.
Methods: French certified and in-training Urologists were invited to participate in an online survey between April and May 2024, including 18 questions assessing demographics, practice trends, awareness of the new guidelines, their dissemination and impact on daily practice.
Defining Kidney Health Dimensions and their Associations with Adverse Outcomes in Persons with Diabetes and Chronic Kidney Disease.
Clin J Am Soc Nephrol
March 2025
Kidney Health Research Collaborative, San Francisco Veterans Affairs Health Care System and University of California, San Francisco; San Francisco, CA.
Background: Individual kidney tubule biomarkers are associated with risks for chronic kidney disease (CKD) progression and mortality in persons with diabetes. Integrating multiple kidney biomarkers using a latent variable method of exploratory factor analysis could define distinct dimensions of kidney health, and their associations with adverse outcomes.
Methods: We conducted a factor analysis of 17 candidate urine and plasma biomarkers in 1,256 participants with diabetes and estimated glomerular filtration rate (eGFR) <60ml/min/1.
Rationale & Objective: Despite national efforts, uptake of home dialysis (peritoneal dialysis or home hemodialysis) remains low. Characteristics of the built environment may differentially impact home dialysis utilization.
Study Design: Retrospective cohort study (2010-2019).
GDF15, EGF, and Neopterin in Assessing Progression of Pediatric Chronic Kidney Disease Using Artificial Intelligence Tools-A Pilot Study.
Int J Mol Sci
March 2025
Department of Nephrology and Transplantation Medicine, Wrocław Medical University, Borowska 213, 50-556 Wrocław, Poland.
Cell-mediated immunity and chronic inflammation are hallmarks of chronic kidney disease (CKD). Growth differentiation factor 15 (GDF15) is a marker of inflammation and an integrative signal in stress conditions. Epidermal growth factor (EGF) is a tubule-specific protein that modulates the regeneration of injured renal tubules.
View Article and Find Full Text PDFAlbuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review.
Circulation
March 2025
Department of Medicine, Boston Medical Center, MA (S.E.C., A.V.).
Albuminuria-increased urine albumin excretion-is associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular risk factors. Many authors have hypothesized that albuminuria reflects widespread endothelial dysfunction, but additional work is needed to uncover whether albuminuria is directly pathologic or causative of cardiovascular disease. Urinary albumin-to-creatinine ratio is an attractive, unifying biomarker of cardiovascular, kidney, and metabolic conditions that may be useful for identifying and monitoring disease trajectory.
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