AI Article Synopsis
- The study concludes that the mean capture time of LDL receptors by coated pits is influenced by their insertion rate function within physiological limits.
- The observed steady-state patterns of unbound receptors align with experimental findings.
- The paper further explores how these results can help estimate the minimum physiological value for the mean capture time of LDL receptors.
Article Abstract
On the basis of this study, it is concluded that within physiological limits the minimum value for the mean capture time of LDL receptors by coated pits must be induced fundamentally by an optimal characterization of their insertion rate function. The corresponding steady-state surface aggregation patterns for the unbound receptors are consistent with experimental observations. The implications of the derived results for the estimation of the minimum physiological value for the referred mean capture time are also discussed.
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| http://dx.doi.org/10.1016/s0025-5564(99)00043-7 | DOI Listing |
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