Objective: Transcranial Doppler is a technique which is being used ever more frequently in the study of intracranial arteries and is very useful in the study of cerebrovascular disease. The typical values of a healthy population in our country are unknown. The aim of this study was determine mean velocity and pulsatility index reference values in a healthy population.
Patients And Method: Transcranial Doppler basal examination was carried out on 118 healthy volunteers without prior haematological or cerebrovascular conditions. Those found to have extracranial arterial stenoses were excluded as were those in whom bilateral temporal bone hyperostosis did not permit insonation in either middle cerebral arteries. The nine intracranial arteries were sounded systematically at fixed depths. The mean and standard deviations of each variable were calculated for side, age group and sex.
Results: 49% were males and average age was of 56 years (range, 21-87 years). A sufficient signal to determine the parameters of the study was obtained in 89% of middle cerebral arteries. Statistically significant differences in mean velocity and pulsatility index were found between age groups and sexes.
Conclusions: Sex and age must be taken into account in establishing typical patterns in transcranial Doppler examination. Our results enable parameters of typical values to be established for the adult population in Spain.
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Am J Physiol Regul Integr Comp Physiol
January 2025
Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, ON, Canada.
This study examined how successive sets of high-intensity leg press (LP) resistance exercise impact the cerebral pressure-flow relationship in untrained males and eumenorrheic females not taking oral contraceptives, and assessed how menstrual cycle (MC) phase influences the cerebral pressure-flow relationship and cerebral hemodynamics (middle cerebral artery blood velocity; MCAv; via transcranial Doppler ultrasound) during and after LP exercise in females. Young adults (11M;11F) performed three sets of leg-press exercises at 90% of their 1-repetition maximum. Data from males and females in early follicular phase were pooled together.
View Article and Find Full Text PDFJ Neurosci Methods
January 2025
IBME, Department of Engineering Science, University of Oxford, Oxford UK.
Background: Cerebrovascular reactivity (CVR) reflects the ability of cerebral blood vessels to adjust their diameter in response to vasoactive stimuli, which is crucial for maintaining brain health. Traditional CVR assessments commonly use a two-point measurement, assuming a linear relationship between cerebral blood flow (CBF) and arterial CO. However, this approach fails to capture non-linear characteristics, particularly the plateaus at extreme CO levels.
View Article and Find Full Text PDFFront Neurol
January 2025
Department of Ultrasound, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.
Objective: Elevated intracranial pressure (ICP), a common complication in traumatic brain injuries (TBI), can lead to optic nerve sheath diameter (ONSD) enlargement and flow spectrum changes from the internal carotid artery (ICA) to middle cerebral artery (MCA). This study will investigate the use of Cervical-Cerebral Arterial Ultrasound (CCAU) for non-invasive ICP assessment and evaluating the related indices' clinical utility in TBI patients with decompressive craniotomy (DC).
Methods: ONSD and flow spectrum changes were measured within 24 h after DC in 106 patients via ultrasonic ONSD measurement and CCAU, simultaneously.
Indian J Crit Care Med
November 2024
Department of Neurology, Neurology and Neurophysiology Center, Vienna, Austria.
Finsterer J. Before the Stump Flow on the TCD in SAH can be Attributed to an SAH Relapse, All Other Possible Causes must be Ruled Out. Indian J Crit Care Med 2024;28(11):1084.
View Article and Find Full Text PDFIndian J Crit Care Med
November 2024
Department of Anesthesia and Critical Care, Amrita School of Medicine, Amrita Vishwa Vidyapeetham, Faridabad, Haryana, India.
Salhotra R. Author Response: Before the Stump Flow on the TCD in SAH can be Attributed to an SAH Relapse all Other Possible Causes must be Ruled Out. Indian J Crit Care Med 2024;28(11):1085.
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