Background: Migraine is one of the most important reason of neurological consultation in Spain.
Objective: The aim of the present study was to analyse the profile of the patient with migraine and investigate epidemiological, clinical and therapeutical differences between migraine with aura o without aura.
Patients And Method: For three consecutive months all patients attending for the first time the Neurology clinics of the Health Service of Aragón, were given a specially designed questionnaire.
Results: 374 patients who met migraine diagnostic criteria were included. They were 10.7% of the all patients. The majority of the patients were women (70%). Patients with migraine without aura were 299 (79.9%). The average age was 33.6 +/- 15.1. The family doctor referred 87% of the patients. Further investigations were requested in 20% of the patients with migraine without aura and 49.3% with aura. Cerebral CT was performed in 5.6% of migraine without aura and in 38.6% of migraine with aura patients, MR in 0.6% of migraine without aura and in 6.6% of migraine with aura patients. Treatment was given to 73% of the migraine patients attending for the first time. Calcium antagonists (45.3%) were the most common used drugs.
Conclusions: Migraine generates a considerable demand for neurological consultations. There are significant differences in investigations requested, treatments and follow-ups of patients with migraine with o without aura.
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Healthcare (Basel)
January 2025
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Migraines are a common neurological disorder that significantly impact women, especially during their reproductive years. Hormonal, neurological, and lifestyle factors shape migraine patterns, with fluctuations during menstruation, pregnancy, perimenopause, and menopause influencing migraine prevalence and severity. This expert opinion explores current challenges, therapeutic strategies, and future directions for personalized care, addressing the limited inclusion of women in clinical research across different life stages.
View Article and Find Full Text PDFNeurol Sci
January 2025
Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Via Mosè Bianchi 90, 20149, Milan, Italy.
Objective: Plasma glial fibrillary acidic protein (pGFAP) and plasma neurofilament light chain (pNfL) levels reflect astrocyte activation and neuronal damage, respectively. Whether these phenomena play a role in migraine is unknown. This study aimed to compare pGFAP and pNfL levels in patients with chronic migraine (CM) and age-matched controls and to analyze their relation with clinical features.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Background: Migraine represents a chronic neurological disorder characterized by high prevalence, substantial disability rates, and significant economic burden. Its pathogenesis is complex, and there is currently no cure. The rapid progress in multi-omics technologies has provided new tools to uncover the intricate pathological mechanisms underlying migraine.
View Article and Find Full Text PDFExplore (NY)
January 2025
Suchangdang Korean Medicine Clinic, Seoul 06084, Republic of Korea.
Background: Migraine is a neurological disorder characterized by severe, unilateral, pulsating headaches with visual, olfactory, and auditory hypersensitivity, as well as autonomic symptoms. Currently, triptans are the standard treatment, but they often fail to relieve symptoms. Herbal medicines are alternative treatments to overcome these limitations.
View Article and Find Full Text PDFJ Physiol
January 2025
Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Patent foramen ovale (PFO), a cardiac anatomical anomaly inducing abnormal haemodynamics, leads to a paradoxical bypass of the pulmonary circulation. PFO closure might alleviate migraines; however, clinical evidence and basic experiments for the relationship are lacking. To explore the effect of PFO on migraine, 371 migraineurs finishing blood tests and contrast transthoracic echocardiography for the detection of PFO were prospectively included.
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