The use of considering Alzheimer's disease as a "primary degenerative dementia" prevails and the disease is thus considered of purely cerebral origin without taking into account the possible effects of the minds of subjects designated Alzheimer sufferers and/or the communicational and relational disorders which may develop between the patient and others. This perspective, which considers the totality of the dementia as a biological phenomenon while overlooking the fact that the human being is also a being of language appears like an act of iatrogenic censure. A consequence of the fear of death so present in our thanatophobic culture, it is related to negation of the elderly subject, too patently mortal, to be recognized and accepted as similar to us. This refusal to identify induces processes of intra-psychic and inter-individual abjection commanded by horror and repulsion. These processes act on all our minds and result in the development of Alzheimer-type dementia syndromes in certain subjects. In this sociopsychogenetic context, the syndromes appear secondary to disorders of identification. The elderly person, denied by those like him and by himself as the image and symbol of death, must live a veritable stage of the disappearing mirror. In contrast to what occurs at the time of the "Lacanian mirror stage" in the child, the elderly subject is pushed out of the symbolic field and towards dementia. Taking the metaphor "senile shipwreck", the author invites the reader to rethink dementia not as a simple cerebral deterioration but rather as a complex disease which is both a disease of the brain and a disease of the mind.
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The purpose of the present study was to evaluate and compare the clinical outcomes of two groups of patients subject to bi-cruciate retaining (BCR) or posterior-stabilized (PS) implants. It was hypothesized that patients treated with BCR prostheses would present higher flexion and better clinical and functional results than those treated with PS implants. This prospective study included thirty-two patients treated for primary knee osteoarthritis and assigned to two matched groups for their demographic characteristics and comorbidities.
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November 2024
Department of Ophthalmology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Objective: To explore the association between retinal microvascular parameters and glaucoma.
Design: Prospective study.
Subjects: The UK Biobank subjects with fundus images and without a history of glaucoma.
Front Endocrinol (Lausanne)
January 2025
Department of Cardiovascular Medicine, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China.
Background: Triglyceride-glucose (TyG) index has been found to be associated with female reproductive disorders, but its relationship with the risk of endometriosis is unknown. Therefore, the aim of this study was to investigate this relationship.
Methods: We performed a two-sample mendelian randomization(MR) analysis to examine the causal effect of TyG index on endometriosis, and inverse variance weighting(IVW) was the main method of analysis.
Front Endocrinol (Lausanne)
January 2025
Department of Metabolic Diseases, Jagiellonian University Medical College, Krakow, Poland.
Background: Continuous glucose monitoring (CGM) improves glycemic control and quality of life. Data on glycemic indices and fear of hypoglycemia (FoH) in newly diagnosed T1DM patients are limited.
Aim: To assess the impact of initiating intermittently scanned CGM (isCGM) within 1-6 months of diagnosis on glycemic control and FoH in adults with T1DM.
J Educ Health Promot
December 2024
Department of Community Medicine, AJ Institute of Medical Sciences, Mangalore, Karnataka, India.
Headache disorders are reported by more than 50% of adults during the previous year in India. In addition to their great prevalence, the World Health Organization lists them as amongthe top ten conditions that are the most disabling. The high disability levels among headaches can also occur with several conditions such as vestibular symptoms, and balance alterations.
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