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Prevention of ovarian hyperstimulation syndrome (OHSS): British Fertility Society policy and practice guideline.
Hum Fertil (Camb)
December 2025
Developmental Biology and Medicine, School of Medical Sciences, The University of Manchester, Manchester, United Kingdom.
This British Fertility Society (BFS) Policy and Practice guideline aims to support clinicians in preventing ovarian hyperstimulation syndrome (OHSS) in patients undergoing gonadotropin ovarian stimulation. A systematic literature search of the medical databases was performed. The Guideline Development Group (GDG) identified the risk factors of OHSS before and during ovarian stimulation.
View Article and Find Full Text PDFSafety and effectiveness of dual trigger (GnRH agonist + HCG) versus HCG alone in patients with high ovarian response.
Am J Transl Res
November 2024
Reproductive Medicine Center, Hunan Provincial Maternal and Child Healthcare Hospital Changsha 410008, Hunan, China.
Objective: To compare the safety and effectiveness between long-term GnRH agonist plus HCG (dual trigger) and HCG trigger alone in high ovarian responders.
Methods: A retrospective study was conducted on clinical data from 314 cases of high ovarian response who underwent in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment at Hunan Provincial Maternal and Child Healthcare Hospital from July 2018 to January 2023. Participants were divided into two groups based on their triggering regimen: the Combined treatment group (GnRH agonist + HCG) and the HCG group (HCG alone).
Outcomes of subsequent IVF cycles among women with PCOS after the first unstimulated IVM treatment: a single-center matched retrospective case-control study.
J Matern Fetal Neonatal Med
December 2024
Centre for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Objective: maturation (IVM) is an advanced technique and an alternative to conventional fertilization (IVF). It is safe, effective, and cost-effective in patients with polycystic ovary syndrome (PCOS). However, no clinical guidelines state that IVM could work without compromised pregnancy outcomes in patients with PCOS.
View Article and Find Full Text PDFOvarian Hyperstimulation Syndrome (OHSS): A Narrative Review and Legal Implications.
J Pers Med
August 2024
School of Law, Polytechnic University of Marche, 60121 Ancona, Italy.
Article Synopsis
- * A comprehensive review of literature from 1990 to 2024 identified risk factors for OHSS, such as age and body weight, and indicated that using a GnRH antagonist reduces the risk compared to traditional protocols, although mild to moderate OHSS can still occur.
- * Effective management of OHSS requires early diagnosis, consideration of psychological impacts, and adherence to evidence-based guidelines for patient care to ensure both safety and legal compliance.
Ischemic events are infrequent in patients with ovarian hyperstimulation syndrome.
J Stroke Cerebrovasc Dis
January 2025
Clinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 520 East 70th Street, Starr Pavilion, 607, New York, NY, 10021, USA. Electronic address:
Background: Case reports describe arterial thrombosis including ischemic stroke associated with severe ovarian hyperstimulation syndrome (OHSS), but the prevalence of major ischemic events during or shortly after OHSS is unknown.
Methods: Using publicly available administrative datasets in the United States between 2015 and 2020, we conducted two separate cross-sectional studies of patients with OHSS. We included all patients with OHSS.
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