Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1727799 | PMC |
| http://dx.doi.org/10.1136/gut.46.1.7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Probing Magnetism in Self-Assembled Organometallic Complexes Using Kondo Spectroscopy.
ACS Nano
January 2025
Physikalisches Institut, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.
Article Synopsis
- Control of individual atomic spins is essential for advancements in spintronics, quantum sensing, and quantum information processing, with scanning tunneling microscopy (STM) being a effective tool for manipulation.
- The research presents a new method for self-assembling magnetic organometallic complexes using iron atoms and specific molecules (Cu(dbm) and FePc) on a silver substrate, effectively forming complexes that mimic metallocenes.
- Magnetic properties of these complexes show a notable Kondo effect, which is explained through density functional theory calculations indicating that the interaction between Fe 3d-orbitals and benzene π-orbitals enhances Kondo screening, offering insights for designing hybrid organometallic systems.
Digital Health Interventions for IBS: Ready for Prime Time?
Dig Dis Sci
December 2024
Division of Gastroenterology, Department of Medicine, Loyola University Medical Center, Chicago, IL, USA.
Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT.
Nat Chem Biol
November 2024
Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
The post-translational modification of intracellular proteins through O-linked β-N-acetylglucosamine (O-GlcNAc) is a conserved regulatory mechanism in multicellular organisms. Catalyzed by O-GlcNAc transferase (OGT), this dynamic modification has an essential role in signal transduction, gene expression, organelle function and systemic physiology. Here, we present Opto-OGT, an optogenetic probe that allows for precise spatiotemporal control of OGT activity through light stimulation.
View Article and Find Full Text PDFSaturation profiling of drug-resistant genetic variants using prime editing.
Nat Biotechnol
November 2024
Department of Pharmacology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Methods to characterize the functional effects of genetic variants of uncertain significance (VUSs) have been limited by incomplete coverage of the mutational space. In clinical oncology, drug resistance arising from VUSs can prevent optimal treatment. Here we introduce PEER-seq, a high-throughput method based on prime editing that can evaluate the functional effects of single-nucleotide variants (SNVs).
View Article and Find Full Text PDFSecondary Dengue Infection Elicits Earlier Elevations in IL-6 and IL-10 Levels.
Int J Mol Sci
October 2024
Instituto de Medicina Experimental (IMEX), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, Buenos Aires 1425, Argentina.
This study investigates the kinetics of interleukine-6 (IL-6) and interleukine-10 (IL-10) levels in dengue virus (DENV) infections during the febrile stage. Viremic patients were categorized into two phases based on anti-DENV IgM presence. Among 259 patients, 71% were in Phase I and 29% in Phase II.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!