Concentration of autoantibodies to human brain NMDA-receptor in blood serum of patients with acute brain ischemic stroke was significantly higher than in healthy persons and patients with other neurological diseases. Average content of cholesterol, lipid peroxides and glutamate in the serum were close in all patient groups investigated. It was suggested that the content of autoantibodies to human brain NMDA-receptor could be used as biochemical criteria for acute brain stroke patient's condition control and their treatment efficiency.

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