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The "central vein sign" to differentiate multiple sclerosis from migraine.
Headache
January 2025
IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Objective: To investigate, in two cohorts including patients with multiple sclerosis (MS) and migraine, (i) the prevalence of the "central vein sign" (CVS), (ii) the spatial distribution of positive CVS (CVS+) lesions, (iii) the threshold of CVS+ lesions able to distinguish MS from migraine with high sensitivity and specificity.
Methods: A total of 70 patients with MS/clinically isolated syndrome and 50 age- and sex-matched patients with migraine underwent a 3-T magnetic resonance imaging scan. The CVS was evaluated according to current guidelines, excluding eight patients with migraine who did not show white matter (WM) lesions.
A preliminary clinical study related to vestibular migraine and cognitive dysfunction.
Front Hum Neurosci
December 2024
The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Background And Purpose: Vestibular migraine (VM) is a common clinical disorder with a genetic predisposition characterized by recurrent episodes of dizziness/vertigo. Patients often complain of the presence of cognitive dysfunction manifestations such as memory loss, which causes great distress in daily life. In this study, we will explore the characteristics and possible risk factors of VM-related cognitive dysfunction by observing the cognitive function and vestibular function status of VM patients, laying the foundation for further exploration of the mechanisms of VM-related cognitive dysfunction.
View Article and Find Full Text PDFEarly trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome.
Exp Neurol
December 2024
Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia. Electronic address:
Wolfram syndrome (WS) is a rare condition caused by homozygous or compound heterozygous mutations in the WFS1 gene primarily. It is diagnosed on the basis of early-onset diabetes mellitus and optic nerve atrophy. Patients complain of trigeminal-like migraines and show deficits in vibration sensation, but the underlying cause is unknown.
View Article and Find Full Text PDFFull moon mesencephalon sign: a transient cytotoxic lesion in a hemodialysis patient with newly diagnosed atrial fibrillation and severe stenosis of the right vertebral artery.
Neurol Sci
December 2024
Department of Neurology, Martin Gropius Hospital, Eberswalde, Germany.
Brain cytotoxic edema is a neuroradiological sign secondary to variegate diseases ranging from migraine to fulminant Listeria rhombencephalitis. The tempestive identification of its underlying cause is vital for an effective treatment as any delay may be fatal. However, the lack of distinctive imaging biomarkers and the paucity of reports pose a significant challenge in its diagnosis and frequently lead to a misdiagnosis particularly with the more common acute ischemic stroke.
View Article and Find Full Text PDFAn objective neurophysiological study of subconcussion in female and male high school student athletes.
Sci Rep
November 2024
Atria Academy of Science and Medicine, New York City, NY, USA.
Article Synopsis
- Recent brain studies indicate that athletes in contact sports experience measurable cognitive and sensory impairments due to cumulative subconcussive impacts throughout the season.
- This study compares a high-contact group to a low-contact control group and includes both male and female high school athletes, using 231 brain scans over a year.
- Results show that while both genders exhibit similar subconcussive impairments, female athletes respond more significantly overall, indicating the importance of monitoring these changes to improve health outcomes related to repetitive head impacts.
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