We describe a case of a three year old unvaccinated child who developed a fulminant diphtheric myocarditis and nephritis four days after the onset of a tonsillar diphtheria. Despite of the administration of antitoxin on day three and four the child died within 48 hours from the beginning of rhythm disturbances. The cardiac involvement rapidly progressed from bradyarrhythmias with the necessity of a temporary pacemaker to ventricular rhythm disturbances with cardiac failure and final ventricular fibrillation.
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http://dx.doi.org/10.1055/s-2008-1043835 | DOI Listing |
Chronobiol Int
January 2025
Laboratory of Braintime, Graduate Institute of Mind, Brain and Consciousness (GIMBC), Taipei Medical University, Taipei, Taiwan.
The intricate relationship between circadian rhythms and mood is well-established. Disturbances in circadian rhythms and sleep often precede the development of mood disorders, such as major depressive disorder (MDD), bipolar disorder (BD), and seasonal affective disorder (SAD). Two primary factors, intrinsic circadian clocks and light, drive the natural fluctuations in mood throughout the day, mirroring the patterns of sleepiness and wakefulness.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
November 2024
Department of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Background: The objective of this article was to explore the use of ChatGPT as a clinical support tool for common arrhythmias.
Methods: This study assessed the feasibility of using ChatGPT as an AI decision-support tool for common rhythm disturbances. The study was conducted using retrospective data collected from electronic medical records (EMRs) of patients with documented rhythm disturbances.
Neurobiol Sleep Circadian Rhythms
May 2025
INCIA, EPHE, Université PSL, Univ Bordeaux, CNRS, 146, Rue Léo Saignat, 33076, Bordeaux, France.
To better understand the relationship between the rest-activity rhythms and cognitive impairments during aging, we assessed the longitudinal changes in the rest-activity rhythms in an elderly population and their possible detrimental effect on the hippocampal network. This was done longitudinally in a rural cohort with two actigraphic assessments and brain imaging examinations, seven years apart. A segmentation of the hippocampus and its related structures was used to assess volumes and functional connectivity in this network based on anatomical and resting state functional data.
View Article and Find Full Text PDFBiofactors
January 2025
Departament de Bioquimica i Biotecnologia, Universitat Rovira i Virgili, Nutrigenomics Research Group, Tarragona, Spain.
Current lifestyles include calorie-dense diets and late-night food intake, which can lead to circadian misalignment. Our group recently demonstrated that sweet treats before bedtime alter the clock system in healthy rats, increasing metabolic risk factors. Therefore, we aimed to assess the impact of the sweet treat consumption time on the clock system in rats fed a cafeteria diet (CAF).
View Article and Find Full Text PDFJ Nutr Biochem
January 2025
Key Laboratory of Endocrinology of National Health Commission, Diabetes Research Center of Chinese Academy of Medical Sciences, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address:
A maternal high-fat diet (HFD) deteriorates the long-term metabolic health of offspring. Circadian rhythms are crucial for regulating metabolism. However, the impact of maternal HFD on the circadian clock in white adipose tissue (WAT) remains unexplored.
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