Unlabelled: To determine the outcome of Pseudomonas aeruginosa bacteremia and to identify risk factors for these infections in our University hospital, 46 cases (65 episodes) of Pseudomonas aeruginosa bacteremia were retrospectively investigated. The most frequent underlying diseases or cases were from Emergency and Critical care center (18 cases, including 11 case of cerebrovascular accident and head injury) followed by hematologic malignancies (11 cases) but none of the HIV infection was included in this study. The overall crude mortality rate was 50% and mortality rate within the first 1 week was 17%. Clinical analysis of those cases revealed that possible risk factors were neutropenia, sever sepsis and prior use of antibiotics (antipseudomonal antibiotics were administered before positive blood culture episodes in 90% cases). But these factors were not statistically significant between dead and survived cases.
Conclusion: To improve the prognosis of Pseudomonas aeruginosa bacteremia, we must change the management of the hospital infection, such as the more rational use of new antipseudomonal antibiotics and the more clean and reasonable management of central venous catheters.
Download full-text PDF |
Source |
---|
Pak J Med Sci
January 2025
Inzimam Ul Haq Postgraduate trainee, Department of ENT, MTI Khyber Teaching Hospital, University Road Peshawar, Pakistan.
Background & Objective: Chronic suppurative otitis media is a fatal condition owing to its propensity for intracranial extension. The inadvertent use of antibiotics has led to resistance among causative organisms. The objectives of this study were to determine causative bacteria, their antibiotic resistance and susceptibility patterns, and their response to antibiotics after a one-month follow-up.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Infectious Diseases Unit, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Purpose: To describe the top three causative organisms of hospital acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in Thailand.
Patients And Methods: This multi-center retrospective cohort study included HAP/VAP patients hospitalized in 2019 in three university-affiliated hospitals and a private hospital in Bangkok, Thailand. Medical records of patients with a documented diagnosis of nosocomial pneumonia (NP) were systematically reviewed to collect data on demographic, clinical, microbiological, and 30-day readmission due to NP.
J Community Hosp Intern Med Perspect
January 2025
Department of Medicine, West Virginia University, House Staff 4Floor HSC-N Morgantown, PO Box 9168, Morgantown, WV, USA.
Implantable cardiac devices, including cardiac pacemakers, are not without risk for infection, carrying a mortality and morbidity of around 5-15%. Gram positive organisms are most common in 91% of cases, whereas gram negative organisms are less common, found in 2% of cases secondary to gram negative organisms other than . Here, we present a rare case of the gram-negative organism leading to a pacemaker site infection.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Cooper University Hospital, Camden, USA.
This case report presents a complex and challenging scenario of recurrent () bacteremia and tricuspid valve endocarditis in a 77-year-old male patient with multiple comorbidities and indwelling medical devices. The patient's medical history was significant for T4 paraplegia, neurogenic bladder requiring a chronic indwelling suprapubic catheter, heart block status post-permanent pacemaker placement, type 2 diabetes mellitus, chronic kidney disease, and chronic sacral wounds. The case highlights the difficulties in managing antibiotic-resistant infections, particularly in patients with implantable devices and chronic wounds.
View Article and Find Full Text PDFCureus
December 2024
Dermatology, University of California, Davis Medical Center, Sacramento, USA.
Melanonychia describes black pigmentation of the nail plate that results from either melanocyte activation (such as infections, local inflammatory disorders, local trauma affecting the nail plate, numerous systemic conditions, and medications) or melanocyte hyperplasia (such as benign neoplasms or malignant tumors) or blood (resulting from a trauma-associated subungual hematoma). The black dyschromia may include not only the nail plate but also the proximal nailfold. The Hutchinson sign refers to black discoloration of both the proximal nailfold and adjacent nail plate when the underlying pigmented lesion is a malignant melanoma.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!