Aims: The distinction between nontuberculous mycobacterial (NTM) lymphadenitis and other causes of cervical lymphadenitis is critical, as different entities call for different treatments. Despite modern diagnostic techniques for NTM infections their prompt and accurate diagnosis is still difficult. We assessed the value of different histological features in diagnosing clinically suggestive NTM cervical lymphadenitis in cases of granulomatous cervical lymphadenitis.
Methods And Results: A retrospective study of 30 patients with a clinical diagnosis of NTM cervical lymphadenitis was carried out. The patients were divided into three subgroups and several histological parameters were examined in each subgroup. A comparison was made with cases of proven tuberculous lymphadenitis. Four histological features (presence of microabscesses, ill-defined granulomas, noncaseating granulomas and a small number of giant cells) were found with significant statistical difference when comparison was made between the NTM group and the tuberculosis group.
Conclusions: A rapid and accurate diagnostic procedure for NTM lymphadenitis is not yet available. Therefore, in the presence of a suggestive clinical picture for NTM lymphadenitis, we propose four histological features which support this diagnosis, thus allowing prompt therapeutic intervention.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1046/j.1365-2559.1999.00787.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Role of Positron Emission Tomography Imaging in Breast Implant Illness.
Plast Reconstr Surg Glob Open
January 2025
From the Section General Internal Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Background: Explantation often alleviates symptoms in women with breast implant illness. However, persistent complaints in some cases may be linked to persistent silicone-induced inflammation from residual silicone particles. Positron emission tomography (PET) imaging could potentially detect this inflammation.
View Article and Find Full Text PDFPyrexia With Pancytopenia: An Uncommon Presentation of Kikuchi Disease.
Cureus
December 2024
Internal Medicine, National Hospital of Sri Lanka, Colombo, LKA.
Kikuchi-Fujimoto disease is a rare systemic illness commonly affecting young females with a higher tendency to occur in the Asian population. Clinical presentation varies with most patients presenting with fever and cervical lymphadenopathy. The patient discussed in this case report presented to a tertiary care hospital in Sri Lanka with a fever for two weeks and palpable cervical lymphadenopathy.
View Article and Find Full Text PDFSyphilitic Lymphadenitis and Clavicle Pathological Fracture Mimicking Malignant Tumor on 18F-FDG PET/CT.
Clin Nucl Med
December 2024
From the Department of Nuclear Medicine, Weifang Traditional Chinese Medicine Hospital, Shandong Second Medical University. Weifang City.
A 66-year-old woman presented with 9 days of left clavicle pain, with no history of recent trauma. CT images showed a left clavicle fracture with a surrounding soft tissue mass. An 18F-FDG PET/CT scan revealed increased FDG uptake in the tonsils, multiple lymph nodes, and the pathologically fractured clavicle, initially suggesting malignancy.
View Article and Find Full Text PDFPredictive factors for drainage in pediatric cervical lymphadenitis: A study of clinical indicators and recovery outcomes.
Am J Otolaryngol
December 2024
Health Scıences Unıversıty Ankara Dr. Sami Ulus Gynecology, Child Health and Diseases Hospital, Department of Pediatrics, Ankara, Türkiye.
Background: The purpose of this study was to investigate the predictive factors for drainage in patients hospitalized with cervical lymphadenitis in the Pediatrics Infectious Diseases Department and to differentiate the recovery time between patients who received antibiotic treatment only and those who received drainage for their lymphadenitis.
Materials And Methods: We retrospectively analyzed 169 patients selected for this study, aged 1 month to 18 years, who were followed up with a diagnosis of cervical lymphadenitis between January 2011 and December 2019. Clinical features such as sex, age, physical examination findings, laboratory findings, imaging findings, and antibiotic treatments were retrospectively reviewed.
Challenges in Differential Diagnosis of Diffuse Gingival Enlargement: Report of Two Representative Cases and Literature Review.
Dent J (Basel)
December 2024
Department of Oral Medicine & Pathology and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens (NKUA), 11527 Athens, Greece.
The etiology of diffuse gingival enlargement is multifactorial, and the definitive diagnosis may be challenging. To highlight the nuances of the differential diagnosis, we present two cases of generalized gingival overgrowth and discuss the diagnostic dilemmas. In the first case, an 82-year-old male with a medical history of hypertension and prostatitis had a chief complaint of symptomatic oral lesions of a 20-day duration, accompanied by fever and loss of appetite.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!