Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Gallibacterium faecale sp. nov., Isolated from Dairy Cow Feces.
Curr Microbiol
January 2025
Korean Collection for Type Cultures, Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, 56212, Republic of Korea.
A facultative anaerobic, Gram-stain-negative, non-motile, rod-shaped bacterial strain AGMB14963 was isolated from the feces of a dairy cow. A 16S rRNA gene sequence-based phylogenetic analysis revealed that strain AGMB14963 belongs to the genus Gallibacterium, with Gallibacterium salpingitidis F150 being the closest species (95.8% 16S rRNA gene sequence similarity).
View Article and Find Full Text PDFRNA splicing: a split consensus reveals two major 5' splice site classes.
Open Biol
January 2025
School of Life Sciences, University of Dundee, Dundee, UK.
The established consensus sequence for human 5' splice sites masks the presence of two major splice site classes defined by preferential base-pairing potentials with either U5 snRNA loop 1 or the U6 snRNA ACAGA box. The two 5' splice site classes are separable in genome sequences, sensitized by specific genotypes and associated with splicing complexity. The two classes reflect the commitment to 5' splice site usage occurring primarily during 5' splice site transfer to U6 snRNA.
View Article and Find Full Text PDFModeling coding sequence design for virus-based expression in tobacco.
Synth Syst Biotechnol
June 2025
Department of Biomedical Engineering, The Iby and Aladar Fleischman Faculty of Engineering, Tel Aviv, Israel.
Transient expression in Tobacco is a popular way to produce recombinant proteins in plants. The design of various expression vectors, delivered into the plant by , has enabled high production levels of some proteins. To further enhance expression, researchers often adapt the coding sequence of heterologous genes to the host, but this strategy has produced mixed results in Tobacco.
View Article and Find Full Text PDFTryptophan metabolism-related gene CYP1B1 serves as a shared biomarker for both Parkinson's disease and insomnia.
Sci Rep
January 2025
Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Zhengzhou, Henan, China.
Parkinson's disease (PD) and insomnia are prevalent neurological disorders, with emerging evidence implicating tryptophan (TRP) metabolism in their pathogenesis. However, the precise mechanisms by which TRP metabolism contributes to these conditions remain insufficiently elucidated. This study explores shared tryptophan metabolism-related genes (TMRGs) and molecular mechanisms underlying PD and insomnia, aiming to provide insights into their shared pathogenesis.
View Article and Find Full Text PDFSequence-Defined DNA Polymers: New Tools for DNA Nanotechnology and Nucleic Acid Therapy.
Acc Chem Res
January 2025
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.
ConspectusStructural DNA nanotechnology offers a unique self-assembly toolbox to construct soft materials of arbitrary complexity, through bottom-up approaches including DNA origami, brick, wireframe, and tile-based assemblies. This toolbox can be expanded by incorporating interactions orthogonal to DNA base-pairing such as metal coordination, small molecule hydrogen bonding, π-stacking, fluorophilic interactions, or the hydrophobic effect. These interactions allow for hierarchical and long-range organization in DNA supramolecular assemblies through a DNA-minimal approach: the use of fewer unique DNA sequences to make complex structures.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!