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Juxtaglomerular Cell Tumor Mimicking Renal Cell Carcinoma on 99m Tc-MIBI SPECT/CT.
Clin Nucl Med
July 2024
From the Department of Neurology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.
Juxtaglomerular cell tumor or reninoma is an extremely rare, typically benign, renin-secreting tumor of the kidney that causes secondary hypertension. We describe 99m Tc-MIBI SPECT/CT findings in a case of juxtaglomerular cell tumor. The renal tumor showed isodensity and photopenia on 99m Tc-MIBI SPECT/CT.
View Article and Find Full Text PDFRegulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines.
Placenta
August 2012
School of Biomedical Sciences & Pharmacy, Mothers & Babies Research Centre, University of Newcastle, Hunter Medical Research Institute & John Hunter Hospital, Newcastle, NSW 2300, Australia.
Objectives: The renin-angiotensin system (RAS) is implicated in placentation. We determined which RAS pathways are present in two trophoblast cell lines (HTR-8/SVneo and BeWo cells) and the effects of cAMP, which stimulates renal renin.
Study Design: The effect of cAMP on RAS gene expression and on prorenin and angiotensin peptides in HTR-8/SVneo and BeWo cells were investigated.
A 22-year-old woman with hypertension and hypokalemia due to a juxtaglomerular cell tumor.
Iran J Kidney Dis
November 2011
Department of Medicine, Nephrology Section, Hasheminejad Clinical Research Development Center, Hasheminejad Kidney Center, Tehran University of Medical Sciences, Tehran, Iran.
Secondary hypertension is responsible for less than 10% of cases of hypertension. If associated with hypokalemia, it may be due to primary or secondary hyperaldostronism, the latter being rarely caused by renin-secreting tumors. We present a 22-year-old woman with a history of hypertension and repeated hypokalemia, who was finally diagnosed with a small renin-secreting tumor after extensive paraclinical workup and imaging studies.
View Article and Find Full Text PDFSecondary hypertension due to a renin-secreting juxtaglomerular cell tumor.
J Formos Med Assoc
March 2010
Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
A juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension. JCT is pathologically benign, and resection of the tumor is curative for hypertension. We report the case of a 17-year-old girl who had hypertension and hypokalemia for 1 year.
View Article and Find Full Text PDFSegmental disorders of the nephron: histopathological and imaging perspective.
Br J Radiol
August 2007
Department of Radiology, University of Texas Health Science Center, San Antonio, TX 78229, USA.
Recent advances in molecular genetics and immunocytochemistry have clarified the cell of origin in many renal disorders. Several renal disorders are thought to involve specific segments of the nephron. Renin-secreting tumours arise from juxtaglomerular cells.
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