The frequencies of micronuclei (MN) in cytokinesis-blocked lymphocytes of 91 steel foundry workers were analysed. On the basis of ambient PAH levels at the work stands and 1-hydroxypyrene concentrations in the urine, the coke-oven workers were the most exposed as compared to the rollers reference group. The difference in results for the two groups studied was not statistically significant, although MN were slightly higher for coke-oven workers. The frequency of MN did not increase with exposure: after some increase in 1-10 years, a decreasing tendency was observed.
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http://dx.doi.org/10.1016/s1383-5718(99)00124-2 | DOI Listing |
Environ Sci Process Impacts
January 2025
Department of Environmental Health, School of Public Health, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
: Coke oven emissions (COEs) are formed in the process of coking production, mainly composed of polycyclic aromatic hydrocarbons (PAHs) and benzene; however, the health impacts of COE exposure in coking workers are not fully clear so far. We aimed to explore the associations of occupational COE exposure with pulmonary function, blood pressure, blood cell parameters, and blood biochemical indices, and to bolster health surveillance and disease prevention and control in coking workers. : We investigated 566 coking workers at a large state-owned enterprise coking plant in Taiyuan, Shanxi, China, measured the concentrations of plasma 16 PAHs and urinary phenol, assessed the health outcomes including pulmonary function, blood pressure, the levels of peripheral hematologic parameters and biochemical indices, and examined the associations of PAH and phenol concentrations with the health outcomes using multiple linear regressions, least absolute shrinkage and selection operator regression (LASSO), and Bayesian kernel machine regression (BKMR).
View Article and Find Full Text PDFInt J Environ Health Res
September 2024
Department of Occupational Health and Occupational Diseases, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
Ecotoxicol Environ Saf
October 2024
MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, NHC Key Laboratory of Pneumoconiosis, Department of Occupational Health, School of Public Health, Shanxi Medical University, Shanxi Key Laboratory of Environmental Health Impairment and Prevention, Xinjiannan Road 56, Taiyuan City, Shanxi Province 030001, China. Electronic address:
Club cell secretory protein (CC16) is considered a biological marker indicating lung epithelial and lung permeability. The joint effect of polycyclic aromatic hydrocarbons (PAHs) exposure on CC16 levels and the association between CC16 levels and long-term lung function changes lacks epidemiological evidence. To investigate the effect of PAHs exposure on plasma CC16 levels and the association between CC16 levels and long-term lung function changes, this study enrolled 307 coke oven workers in 2014, measured their baseline concentrations of urinary PAHs metabolites and plasma CC16, with follow-up after nine years.
View Article and Find Full Text PDFEnviron Pollut
May 2024
Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, Guangdong, China; School of Public Health, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China. Electronic address:
Background: Polycyclic aromatic hydrocarbons (PAHs) are well-acknowledged pro-inflammatory chemicals, but their associations with blood cell-based inflammatory biomarkers need further investigation. Moreover, the effects and mechanisms of essential metals on PAH-related inflammation remain poorly understood.
Objects: To elucidate the associations of PAHs on inflammatory biomarkers, as well as the effects and mechanisms of essential metals on these associations.
Cent Eur J Public Health
December 2023
Department of Biology, Faculty of Humanities and Natural Sciences, University of Presov, Presov, Slovak Republic.
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