History And Clinical Findings: A 21-year-old man was admitted twice within half-a-year because of fatigue and increasing dyspnoea. Both times the chest x-ray showed extensive pulmonary infiltrates. Clinical remission occurred within a few days of starting antibiotic treatment.

Investigations: During the second admission an increased titre for antibodies against glomerular basement membrane was discovered (2560 U/ml); renal functions were normal, but there was haematuria. Renal biopsy revealed linear deposits of IgG along the glomerular basement membrane.

Diagnosis, Treatment And Course: The pattern of findings indicated Goodpasture's syndrome. Immunosuppressive treatment and plasma separation did not have to be performed because spontaneous remission occurred within a few days.

Conclusion: This case demonstrates that spontaneous remission may occur in Goodpasture's syndrome.

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http://dx.doi.org/10.1055/s-2007-1024514DOI Listing

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