Purpose: The aim of this investigation was to evaluate a prototype noncontact pneumatic esthesiometer for measuring sensitivity of the eye.
Methods: To evaluate the instrument's repeatability, central corneal sensitivity was recorded on two separate occasions with a 24-h interval between the two measures. In a separate experiment, corneal edema was induced with a thick hydrogel lens, and the eye was closed and patched. Corneal sensitivity was measured before wearing the lenses for 3 h, immediately after lens removal, and 15 min later. Corneal sensitivity also was measured before the instillation of a single drop of proparacaine (Alcaine, 0.5%) and at 2 and 18 min later. Sensitivity was measured at the corneal apex and at a temporal conjunctival location 3 mm from the limbus.
Results: A high correlation was found between days 1 and 2 (r = 0.90; p = 0.0001). The coefficient of repeatability (COR = 0.87 mm Hg) showed that 95% of the difference between test and retest measures were between +/-0.87 mm Hg. Corneal sensitivity decreased by 55% after lens-induced corneal swelling and by 159% after instillation of the topical anesthetic. Central corneal sensitivity was found to be significantly higher than that of the temporal conjunctiva (p = 0.0001).
Conclusion: We conclude that this pneumatic esthesiometer provides repeatable and reliable measures of ocular-surface sensitivity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00003226-199911000-00009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A New Method to Measure Ocular Surface Sensitivity: Repeatability and Reproducibility of the Liquid Jet Esthesiometer.
Eye Contact Lens
November 2024
School of Optometry and Vision Science (K.E., F.S., B.T., J.C., B.G.), University of New South Wales, Sydney, Australia; and Department of Optics and Optometry and Vision Sciences (C.T.-E.), University of Valencia, Valencia, Spain.
Objectives: To assess the reliability of the liquid jet esthesiometer (LJA) for measurement of corneal sensitivity.
Methods: Two separate studies were conducted to assess intrasession repeatability (study 1) and intersession reproducibility (study 2) of corneal sensitivity measured using the LJA. Thirty participants (13 female and 17 male participants, age 23±6 years) participated in study 1 and another 30 (18 female and 12 male participants, 35±10 years) participated in study 2.
Size Matters: A Comparative Study on Midday Fogging and Lens Settling in Patients With Keratoconus Wearing Mini-Scleral Lenses With Two Different Diameters.
Eye Contact Lens
November 2024
Department of Ophthalmology (E.B.V.), Kocaeli Kandıra M. Kazım Dinç State Hospital, Kocaeli, Turkey; Department of Ophthalmology (S.A.T.), Marmara University Medical School, Istanbul, Turkey; and Department of Ophthalmology and Visual Sciences (A.E.T.), West Virginia University Eye Institute, Morgantown, WV.
Purpose: The objective of this study was to compare the changes in postlens fluid optical density, timing and quantity of lens settling, and the clinical performance between two different mini-scleral lenses.
Methods: Seventeen eyes of 10 patients with keratoconus were fitted with a 15-mm mini-scleral lens (AirKone Scleral Lenses; Laboratoire LCS, Normandy, France), and 15 eyes of 10 patients with keratoconus were fitted with 16.5-mm mini-scleral lenses (Misa Lenses; Microlens Contactlens Technology, Arnhem, The Netherlands).
Controlling of Applied Force and Cornea Displacement Estimation in Robotic Corneal Surgery With a Gripper Surgical Instrument.
Int J Med Robot
February 2025
Faculty of Health, Education, Medicine and Social Care, Medical Technology Research Centre, The Institute of Excellence in Robotic Surgery, Anglia Ruskin University, Chelmsford, UK.
Background: The human eye consists of highly sensitive, hydrated, and relatively thin tissues, making precise control and accurate force estimation crucial in robotic eye surgery. This paper introduces a novel control method and state observer designed for a gripper surgical instrument used on the external ocular surface during robotic eye surgery.
Methods: A novel state observer, operating in tandem with the controller, estimates the applied force.
Compartmental analysis of retinal vascular parameters and thickness in myopic eyes using SS-OCTA.
Front Med (Lausanne)
December 2024
Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- The study examined how myopia affects the thickness and structure of retinal blood vessels using advanced imaging technology in 100 participants.
- The findings revealed that individuals with high myopia had significantly lower vessel density and thinner retinal layers, particularly noticeable in the superficial and nerve fiber layers.
- There was a noted correlation between certain ocular parameters, such as axial length to curvature radius ratio, and retinal thickness in non-high myopic eyes, while high myopic eyes showed less correlation in these aspects.
Association of Blood Pressure and Retinal Nerve Fiber Layer Rates of Thinning in Patients with Moderate to Advanced Glaucoma.
Ophthalmol Glaucoma
January 2025
Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California. Electronic address:
Purpose: Investigate the influence of baseline blood pressure (BP) on retinal nerve fiber layer (RNFL) rates of change (RoC) in glaucoma patients with central damage or moderate to severe disease.
Design: Prospective cohort study.
Participants: 110 eyes with ≥4 RNFL optical coherence tomography scans and ≥2 years of follow-up.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!