The goals of this study were to examine the following hypotheses: (a) there is a difference between the theoretically calculated (McMahon and Cheng, 1990. Journal of Biomechanics 23, 65-78) and the kinematically measured length changes of the spring-mass model and (b) the leg spring stiffness, the ankle spring stiffness and the knee spring stiffness are influenced by running speed. Thirteen athletes took part in this study. Force was measured using a "Kistler" force plate (1000 Hz). Kinematic data were recorded using two high-speed (120 Hz) video cameras. Each athlete completed trials running at five different velocities (approx. 2.5, 3.5, 4.5, 5.5 and 6.5 m/s). Running velocity influences the leg spring stiffness, the effective vertical spring stiffness and the spring stiffness at the knee joint. The spring stiffness at the ankle joint showed no statistical difference (p < 0.05) for the five velocities. The theoretically calculated length change of the spring-mass model significantly (p < 0.05) overestimated the actual length change. For running velocities up to 6.5 m/s the leg spring stiffness is influenced mostly by changes in stiffness at the knee joint.
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http://dx.doi.org/10.1016/s0021-9290(99)00133-5 | DOI Listing |
Rev Sci Instrum
January 2025
Pen-Tung Sah Institute of Micro-Nano Science and Technology, Xiamen University, Xiamen, Fujian 361005, China.
A two-degree-of-freedom bistable energy harvester with a spring-magnet oscillator designed for ultra-low frequency vibration energy harvesting is presented in this paper. It combines magnetic plucking frequency upconversion and a variable potential function to achieve a high-efficiency response while also being suitably installed for applications with spatial limitations. A lumped parameter model of the piezoelectric energy harvester and the magnetic dipoles is applied to develop the theoretical model for the system.
View Article and Find Full Text PDFJ Clin Hypertens (Greenwich)
January 2025
Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, New York, USA.
Dyslipidemia, abnormal levels of lipids in the bloodstream, is associated with cardiovascular disease risk (CVD). The purpose of this study was to evaluate the effects of dyslipidemia on cardiometabolic health in relatively young, healthy adults. Participants were 54 healthy males and females aged 18-60 years.
View Article and Find Full Text PDFJOR Spine
March 2025
Beijing Key Laboratory for Design and Evaluation Technology of Advanced Implantable & Interventional Medical Devices, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering Beihang University Beijing China.
Background: Growth rods are the gold standard for treating early-onset scoliosis (EOS). However, current treatments with growth rods do not optimize spinal growth in EOS patients, and frequent distraction surgeries significantly increase complications, imposing considerable economic and psychological burdens on patients. An improved growth rod is urgently required to address the need for dynamic growth and external regulation.
View Article and Find Full Text PDFNat Neurosci
January 2025
Department of Cellular Neurobiology, University of Göttingen, Göttingen, Germany.
The sensation of mechanical stimuli is initiated by elastic gating springs that pull open mechanosensory transduction channels. Searches for gating springs have focused on force-conveying protein tethers such as the amino-terminal ankyrin tether of the Drosophila mechanosensory transduction channel NOMPC. Here, by combining protein domain duplications with mechanical measurements, electrophysiology, molecular dynamics simulations and modeling, we identify the NOMPC gating-spring as the short linker between the ankyrin tether and the channel gate.
View Article and Find Full Text PDFCirc Res
January 2025
Department of Integrative Pathophysiology, Medical Faculty Mannheim, DZHK Partnersite Mannheim-Heidelberg, University of Heidelberg, Germany (S.L.).
This review examines the giant elastic protein titin and its critical roles in heart function, both in health and disease, as discovered since its identification nearly 50 years ago. Encoded by the TTN (titin gene), titin has emerged as a major disease locus for cardiac disorders. Functionally, titin acts as a third myofilament type, connecting sarcomeric Z-disks and M-bands, and regulating myocardial passive stiffness and stretch sensing.
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