Objective: To analyze the factors involved in the functional prognosis of stroke patients three months after onset.
Patients And Methods: We made a prospective study of 288 patients with non-transient strokes who had been admitted consecutively to our hospital. Data was collected on a standardized questionnaire: age, sex, risk factors, latency of admission, interval of neurological attention (INA), severity of defect (classified on the Scandinavian scale: slight-moderate: SSS > 30/serious: SSS < or = 30), stay in hospital, development of complications and previous quality of life, after seven and ninety days. Two groups were considered according to Barthel's index (BI): acceptable recuperation: BI > 60 and poor recuperation BI < or = 60.
Results: The average age was 70.72 years and the latency of admission was 9.71 hours. After three months the functional prognosis was good in 145 patients. On bivariate analysis the latency of admission, severity of the stroke, age, development of complications, INA and BI, one week later were significant. Multivariate analysis confirmed as independent indicators of poor prognosis after 90 days: advanced age of the patient (p = 0.006), the development of complications (p = 0.0235), serious neurological defect (p = 0.0274) and the BI after seven days (p = 0.006).
Conclusions: Advanced age of the patient, the extent of the defect and appearance of complications whilst in hospital were associated with poorer quality of life after three months. The INA > 6 hours also had a negative influence, although it was not confirmed to be an independent variable.
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Int Urol Nephrol
January 2025
Department of Urology and Urosurgery, Medical Faculty Mannheim, University Medical Centre Mannheim (UMM), University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Baden-Württemberg, Germany.
Purpose: To identify prognostic factors for overall survival (OS) and develop a prognostic score in patients receiving docetaxel in metastatic castration-resistant prostate cancer (mCRPC).
Methods: Retrospective analysis was conducted on mCRPC patients treated with docetaxel at a German tertiary center between March 2010 and November 2023. Prognostic clinical and laboratory factors were analyzed using uni- and multivariable logistic regression.
Prev Sci
January 2025
Academy of Future Education, Xi'an Jiaotong-Liverpool University, No.8 Chongwen Road, Suzhou, 215123, Jiangsu Province, China.
Parental emotion socialization is crucial to children's development, yet emotion-focused parenting programs are scarce in non-Western contexts. In this study, we developed a four-week emotion-focused parenting program based on the principles of emotion coaching for Chinese families with preschool-aged children. This program integrated parent group sessions with home-based parent-child shared reading.
View Article and Find Full Text PDFActa Neurochir (Wien)
January 2025
Department of Neurosurgery and Department of Neuroscience, Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment, Xiamen Key Laboratory of Brain Center, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Purpose: To investigate the technique for dorsal median sulcus (DMS) mapping and assess its application value in preserving dorsal columnn (DC) function during intramedullary space occupying surgery based on a single-center experience.
Methods: A retrospective analysis was conducted on 41 cases of intramedullary spinal cord tumor admitted to the Department of Neurosurgery at the First Affiliated Hospital of Xiamen University from March 2017 to August 2023. All included cases underwent intraoperative electrophysiological monitoring, and were divided into a study group (n = 18) and a control group (n = 23), based on whether DMS mapping technique was utilized.
The ejaculatory reflex consists of emission and expulsion, with the latter involving rhythmic muscular contractions that propel seminal fluid. Botulinum toxin, through its inhibitory effects, has been hypothesized to improve premature ejaculation (PE). This study evaluates high-quality evidence on botulinum toxin-A injections into the bulbospongiosal muscle as a treatment for PE.
View Article and Find Full Text PDFSurg Endosc
January 2025
Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, Taiwan.
Background: This study aimed to investigate the clinical characteristics and esophageal motility of patients with gastric cardia submucosal tumors (SMTs) and the associated changes after endoscopic resection based on high-resolution impedance manometry (HRIM).
Methods: From our electronic database, we identified patients who underwent pre-operative evaluation of gastric cardia SMTs between 2015 and 2023. All patients completed standardized symptom questionnaires and underwent endoscopic ultrasonography and HRIM.
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